hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11946.1
Complex Portal: CPX-21649
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IGDCC4 | Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36) | 4 | UniProt NCBI |
| PTPRB | Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP) | 5 | UniProt NCBI |
| SGCE | Epsilon-sarcoglycan (Epsilon-SG) | 5 | UniProt NCBI |
| HCRTR2 | Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-389397 | 0.0499436884912 | 0.25 | HCRTR2 | Orexin and neuropeptides FF and QRFP bind to their respective receptors |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SGCE | IGDCC4 | 0.933 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| IGDCC4 | HCRTR2 | 0.89 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| IGDCC4 | PTPRB | 0.821 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SGCE | PTPRB | 0.039 | 0.062 | bioplex3_WMM gupta_WMM WMM_only |
Related Complexes