hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11961.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AKR7A2 | Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase) | 5 | UniProt NCBI |
| ACAT1 | Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2) | 5 | UniProt NCBI |
| HABP4 | Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Hyaluronan-binding protein 4) (Ki-1/57 intracellular antigen) | 5 | UniProt NCBI |
| AKR7L | Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) | 5 | UniProt NCBI |
| UPF2 | Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2) | 5 | UniProt NCBI |
| AKR7A3 | Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP699 | 5.36057998926e-05 | 0.5 | AKR7A2 AKR7A3 | Aflatoxin B1 metabolism |
| REAC:R-HSA-5423646 | 0.0013924419067 | 0.5 | AKR7A2 AKR7A3 | Aflatoxin activation and detoxification |
| KEGG:00980 | 0.00426927356048 | 0.5 | AKR7A2 AKR7A3 | Metabolism of xenobiotics by cytochrome P450 |
| WP:WP702 | 0.0228199530946 | 0.5 | AKR7A2 AKR7A3 | Metapathway biotransformation Phase I and II |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AKR7A2 | AKR7A3 | 0.999 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| AKR7A3 | AKR7L | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AKR7A2 | AKR7L | 0.987 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AKR7L | UPF2 | 0.943 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AKR7L | HABP4 | 0.879 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AKR7A2 | ACAT1 | 0.862 | 0.054 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| AKR7L | ACAT1 | 0.128 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| UPF2 | HABP4 | 0.074 | 0.122 | bioplex3_WMM WMM_only |
| AKR7A3 | ACAT1 | 0.05 | 0.102 | bioplex3_HEK293 bioplex () bioplex3_WMM |
| ACAT1 | HABP4 | 0.005 | 0.042 | bioplex3_WMM WMM_only |
Related Complexes