List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11964.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
HRNR	Hornerin	5	UniProt   NCBI
KRT6A	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)	5	UniProt   NCBI
CIDEA	Lipid transferase CIDEA (Cell death activator CIDE-A) (Cell death-inducing DFFA-like effector A)	5	UniProt   NCBI
KRT6B	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0025248	0.000200620835246	0.5	KRT6A KRT6B	Eruptive vellus hair cyst
HP:0012035	0.000200620835246	0.5	KRT6A KRT6B	Steatocystoma multiplex
HP:0007490	0.000334337547576	0.5	KRT6A KRT6B	Linear arrays of macular hyperkeratoses in flexural areas
HP:0030268	0.000334337547576	0.5	KRT6A KRT6B	Hyperplastic callus formation
HP:0008401	0.000501460556964	0.5	KRT6A KRT6B	Onychogryposis of toenails
HP:0040036	0.000935888865729	0.5	KRT6A KRT6B	Onychogryposis of fingernail
HP:0007446	0.00120317586686	0.5	KRT6A KRT6B	Palmoplantar blistering
HP:0030318	0.00150383256857	0.5	KRT6A KRT6B	Angular cheilitis
HP:0007410	0.00183784982408	0.5	KRT6A KRT6B	Palmoplantar hyperhidrosis
HPA:0461403	0.00188974273454	0.5	KRT6A KRT6B	skin 1; cells in corneal layer[High]
HP:0006089	0.00220521848756	0.5	KRT6A KRT6B	Palmar hyperhidrosis
HPA:0471403	0.00229312816095	0.5	KRT6A KRT6B	skin 2; cells in corneal layer[High]
HP:0100798	0.00350734148159	0.5	KRT6A KRT6B	Fingernail dysplasia
HP:0030766	0.00350734148159	0.5	KRT6A KRT6B	Ear pain
HP:0200040	0.00350734148159	0.5	KRT6A KRT6B	Epidermoid cyst
HP:0001818	0.00400802433742	0.5	KRT6A KRT6B	Paronychia
HPA:0461402	0.00620298148036	0.5	KRT6A KRT6B	skin 1; cells in corneal layer[>=Medium]
HP:0025245	0.00701084122037	0.5	KRT6A KRT6B	Cutaneous cyst
HP:0100803	0.00771122114953	0.5	KRT6A KRT6B	Abnormality of the periungual region
HP:0033800	0.00844485194452	0.5	KRT6A KRT6B	Blistering by anatomical location
HP:0002745	0.0108451581837	0.5	KRT6A KRT6B	Oral leukoplakia
HP:0025125	0.0108451581837	0.5	KRT6A KRT6B	White lesion of the oral mucosa
HP:0001805	0.0117117011059	0.5	KRT6A KRT6B	Onychogryposis
HPA:0471402	0.0126567274704	0.5	KRT6A KRT6B	skin 2; cells in corneal layer[>=Medium]
HP:0007502	0.0135443934278	0.5	KRT6A KRT6B	Follicular hyperkeratosis
HPA:0461401	0.0136651670059	0.5	KRT6A KRT6B	skin 1; cells in corneal layer[>=Low]
HP:0012514	0.018706736024	0.5	KRT6A KRT6B	Lower limb pain
HP:0000695	0.0198386649826	0.5	KRT6A KRT6B	Natal tooth
HP:0046506	0.021003726131	0.5	KRT6A KRT6B	Pain in head and neck region
REAC:R-HSA-6809371	0.022534212454	0.5	KRT6A KRT6B	Formation of the cornified envelope
REAC:R-HSA-6805567	0.0239057396727	0.5	KRT6A KRT6B	Keratinization
HP:0006288	0.028689358225	0.5	KRT6A KRT6B	Advanced eruption of teeth
HPA:0461453	0.0292462264975	0.5	KRT6A KRT6B	skin 1; hair follicles[High]
HPA:0471401	0.0328453637696	0.5	KRT6A KRT6B	skin 2; cells in corneal layer[>=Low]
HP:0100825	0.0329787201379	0.5	KRT6A KRT6B	Cheilitis
HP:0009763	0.0391604009626	0.5	KRT6A KRT6B	Limb pain



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
KRT6A	KRT6B	0.964	0.48	hein_WMM     youn_WMM     gupta_WMM     WMM_only     boldt_WMM
HRNR	KRT6A	0.828	0.252	hein_WMM     youn_WMM     gupta_WMM     WMM_only     boldt_WMM
HRNR	CIDEA	0.824		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
HRNR	KRT6B	0.575	0.352	youn_WMM     gupta_WMM     WMM_only     boldt_WMM





Related Complexes

Genename	Complexes
HRNR	huMAP3_01769.1 huMAP3_04874.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11079.1 huMAP3_11964.1
KRT6A	huMAP3_01811.1 huMAP3_11343.1 huMAP3_11964.1
CIDEA	huMAP3_11964.1
KRT6B	huMAP3_01811.1 huMAP3_11964.1 huMAP3_15329.1