hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11975.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LRRC32 | Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32) | 5 | UniProt NCBI |
| RTN4R | Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) | 5 | UniProt NCBI |
| FMOD | Fibromodulin (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) | 5 | UniProt NCBI |
| TLR2 | Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282) | 5 | UniProt NCBI |
| STK11IP | Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1) | 5 | UniProt NCBI |
| CCDC181 | Coiled-coil domain-containing protein 181 | 4 | UniProt NCBI |
| TNFRSF10D | Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04350 | 0.0376568492551 | 0.285714285714 | LRRC32 FMOD | TGF-beta signaling pathway |
| WP:WP5143 | 0.0433840554919 | 0.142857142857 | FMOD | GDNF signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FMOD | LRRC32 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LRRC32 | TNFRSF10D | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LRRC32 | RTN4R | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FMOD | CCDC181 | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| STK11IP | FMOD | 0.946 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| STK11IP | TLR2 | 0.915 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| STK11IP | LRRC32 | 0.912 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TNFRSF10D | RTN4R | 0.902 | bioplex3_WMM WMM_only | |
| FMOD | RTN4R | 0.902 | bioplex3_WMM WMM_only | |
| FMOD | TNFRSF10D | 0.902 | bioplex3_WMM WMM_only | |
| STK11IP | CCDC181 | 0.045 | bioplex3_WMM WMM_only | |
| STK11IP | TNFRSF10D | 0.026 | 0.08 | bioplex3_WMM WMM_only |
| STK11IP | RTN4R | 0.026 | bioplex3_WMM WMM_only |
Related Complexes