hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11984.1
Complex Portal: CPX-20573
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BMP5 | Bone morphogenetic protein 5 (BMP-5) | 5 | UniProt NCBI |
| HBB | Hemoglobin subunit beta (Beta-globin) (Hemoglobin beta chain) [Cleaved into: LVV-hemorphin-7; Spinorphin] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004817 | 0.0499436884913 | 0.5 | HBB | Drug-sensitive hemolytic anemia |
| HP:0005546 | 0.0499436884913 | 0.5 | HBB | Increased red cell osmotic resistance |
| HP:0011905 | 0.0499436884913 | 0.5 | HBB | Reduced hemoglobin A |
| HP:0011906 | 0.0499436884913 | 0.5 | HBB | Reduced beta/alpha synthesis ratio |
| HP:0011981 | 0.0499436884913 | 0.5 | HBB | Pigment gallstones |
| HP:0020058 | 0.0499436884913 | 0.5 | HBB | Abnormal red blood cell count |
| HP:0020059 | 0.0499436884913 | 0.5 | HBB | Increased red blood cell count |
| HP:0030058 | 0.0499436884913 | 0.5 | HBB | Sickled erythrocytes |
| HP:0031090 | 0.0499436884913 | 0.5 | HBB | Finger dactylitis |
| HP:0034280 | 0.0499436884913 | 0.5 | HBB | Target cells |
| HP:0045048 | 0.0499436884913 | 0.5 | HBB | Increased HbA2 hemoglobin |
| HP:0200023 | 0.0499436884913 | 0.5 | HBB | Priapism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HBB | BMP5 | 0.886 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| BMP5 | huMAP3_11984.1 huMAP3_13522.1 |
| HBB | huMAP3_04556.1 huMAP3_06991.1 huMAP3_10486.1 huMAP3_11984.1 huMAP3_13522.1 huMAP3_15040.1 |