hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11991.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2) | 5 | UniProt NCBI |
| TMED6 | Transmembrane emp24 domain-containing protein 6 (p24 family protein gamma-5) (p24gamma5) | 3 | UniProt NCBI |
| SLC35A2 | UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) | 5 | UniProt NCBI |
| NETO2 | Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5619072 | 0.0498224659464 | 0.333333333333 | SLC35A2 | Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) |
| CORUM:6625 | 0.0499402709677 | 0.333333333333 | SLC35A2 | MGAT4B-SLC35A2(splice variant 1) complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PLCG2 | SLC35A2 | 0.999 | 0.046 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| SLC35A2 | TMED6 | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TMED6 | NETO2 | 0.855 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC35A2 | NETO2 | 0.107 | 0.088 | gupta_WMM WMM_only |
Related Complexes