hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11995.1
Complex Portal: CPX-14064
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHP2 | Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520) | 5 | UniProt NCBI |
| ASAH1 | Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7098 | 0.0249718442457 | 0.5 | ASAH1 | ASAH1-NR5A1 complex |
| WP:WP5179 | 0.049750157242 | 0.5 | ASAH1 | Biosynthesis and turnover of 1 deoxy sphingoid bases |
| CORUM:7099 | 0.0499419797295 | 0.5 | ASAH1 | ASAH1-NR5A1-SAPD complex |
| HP:0006575 | 0.0499436884913 | 0.5 | ASAH1 | Intrahepatic cholestasis with episodic jaundice |
| HP:0034053 | 0.0499436884913 | 0.5 | ASAH1 | Decreased acid ceramidase activity |
| HP:0040139 | 0.0499436884913 | 0.5 | ASAH1 | Lipogranulomatosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ASAH1 | CHP2 | 0.927 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes