hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12005.1
Complex Portal: CPX-22878
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ALS2CL | ALS2 C-terminal-like protein | 5 | UniProt NCBI |
| ALS2 | Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) | 5 | UniProt NCBI |
| STXBP6 | Syntaxin-binding protein 6 (Amisyn) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876198 | 0.0220121799777 | 0.666666666667 | ALS2CL ALS2 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | ALS2CL ALS2 | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALS2 | STXBP6 | 0.994 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ALS2CL | ALS2 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ALS2CL | huMAP3_01438.1 huMAP3_12005.1 |
| ALS2 | huMAP3_01438.1 huMAP3_12005.1 |
| STXBP6 | huMAP3_06315.1 huMAP3_08929.1 huMAP3_10587.1 huMAP3_10601.1 huMAP3_12005.1 huMAP3_13160.1 |