hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12024.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARF3 | ADP-ribosylation factor 3 | 5 | UniProt NCBI |
| ARF4 | ADP-ribosylation factor 4 | 5 | UniProt NCBI |
| ARF1 | ADP-ribosylation factor 1 (EC 3.6.5.2) | 5 | UniProt NCBI |
| ARF5 | ADP-ribosylation factor 5 | 5 | UniProt NCBI |
| DDX60 | Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6811434 | 1.24109632959e-06 | 0.8 | ARF4 ARF3 ARF5 ARF1 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 1.41183765805e-06 | 0.8 | ARF4 ARF3 ARF5 ARF1 | COPI-mediated anterograde transport |
| REAC:R-HSA-8856688 | 4.24686934885e-06 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-199977 | 7.07988042852e-06 | 0.8 | ARF4 ARF3 ARF5 ARF1 | ER to Golgi Anterograde Transport |
| KEGG:04144 | 1.45802271707e-05 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Endocytosis |
| REAC:R-HSA-948021 | 1.49011277783e-05 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-6811442 | 2.36864607463e-05 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| REAC:R-HSA-446203 | 0.00011004914384 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Asparagine N-linked glycosylation |
| REAC:R-HSA-1660514 | 0.0018206657072 | 0.4 | ARF3 ARF1 | Synthesis of PIPs at the Golgi membrane |
| REAC:R-HSA-199991 | 0.00183945180572 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.00228321498701 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Vesicle-mediated transport |
| GO:0003924 | 0.0180995584082 | 0.8 | ARF4 ARF3 ARF5 ARF1 | GTPase activity |
| GO:0006890 | 0.018748745536 | 0.6 | ARF4 ARF3 ARF5 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| WP:WP5224 | 0.0316649111647 | 0.4 | ARF1 ARF5 | 2q37 copy number variation syndrome |
| REAC:R-HSA-597592 | 0.0380600523345 | 0.8 | ARF4 ARF3 ARF5 ARF1 | Post-translational protein modification |
| REAC:R-HSA-1483255 | 0.0384836492499 | 0.4 | ARF3 ARF1 | PI Metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARF5 | ARF1 | 0.998 | 0.296 | bioplex3_HEK293 Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction |
| ARF3 | ARF5 | 0.993 | 0.724 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
| ARF5 | ARF4 | 0.991 | 0.534 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
| ARF4 | ARF1 | 0.968 | 0.286 | Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| ARF3 | ARF1 | 0.878 | 0.312666666667 | bioplex3_WMM WMM_only boldt_WMM |
| ARF3 | DDX60 | 0.847 | 0.204 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ARF3 | ARF4 | 0.314 | 0.774 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only |
| ARF4 | DDX60 | 0.006 | 0.122 | bioplex3_HCT116 fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| ARF3 | huMAP3_03629.1 huMAP3_11827.1 huMAP3_12024.1 |
| ARF4 | huMAP3_03629.1 huMAP3_12024.1 |
| ARF1 | huMAP3_03629.1 huMAP3_12024.1 |
| ARF5 | huMAP3_03629.1 huMAP3_05921.1 huMAP3_12024.1 |
| DDX60 | huMAP3_04171.1 huMAP3_04514.1 huMAP3_11478.1 huMAP3_11827.1 huMAP3_12024.1 huMAP3_12586.1 huMAP3_12846.1 |