hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12026.1
Complex Portal: CPX-12973
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NEO1 | Neogenin (Immunoglobulin superfamily DCC subclass member 2) | 5 | UniProt NCBI |
| MFAP5 | Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2) | 5 | UniProt NCBI |
| TNF | Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4747 | 0.000973512535349 | 0.666666666667 | NEO1 TNF | Netrin UNC5B signaling pathway |
| KEGG:04350 | 0.0028446957576 | 0.666666666667 | NEO1 TNF | TGF-beta signaling pathway |
| CORUM:6684 | 0.0499402709677 | 0.333333333333 | TNF | TNFR2 signaling complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NEO1 | MFAP5 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TNF | NEO1 | 0.874 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes