hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12027.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IFI44 | Interferon-induced protein 44 (p44) (Microtubule-associated protein 44) | 3 | UniProt NCBI |
| IFNAR2 | Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2) | 5 | UniProt NCBI |
| IFI44L | Interferon-induced protein 44-like | 4 | UniProt NCBI |
| IFNA21 | Interferon alpha-21 (IFN-alpha-21) (Interferon alpha-F) (LeIF F) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4912 | 0.00110807642161 | 0.5 | IFNAR2 IFNA21 | SARS coronavirus and innate immunity |
| WP:WP4558 | 0.00151495259867 | 0.5 | IFNAR2 IFNA21 | Overview of interferons mediated signaling pathway |
| WP:WP4341 | 0.00495989715897 | 0.5 | IFNAR2 IFI44L | Non genomic actions of 1 25 dihydroxyvitamin D3 |
| GO:0009615 | 0.00650116044211 | 1.0 | IFI44 IFNA21 IFI44L IFNAR2 | response to virus |
| WP:WP75 | 0.00862655865142 | 0.5 | IFNAR2 IFNA21 | Toll like receptor signaling pathway |
| KEGG:04620 | 0.00931062778609 | 0.5 | IFNAR2 IFNA21 | Toll-like receptor signaling pathway |
| KEGG:04650 | 0.014619629343 | 0.5 | IFNAR2 IFNA21 | Natural killer cell mediated cytotoxicity |
| KEGG:05162 | 0.0189154103852 | 0.5 | IFNAR2 IFNA21 | Measles |
| WP:WP4630 | 0.01895043011 | 0.5 | IFNAR2 IFNA21 | Measles virus infection |
| KEGG:04630 | 0.0211069184789 | 0.5 | IFNAR2 IFNA21 | JAK-STAT signaling pathway |
| KEGG:05160 | 0.0211069184789 | 0.5 | IFNAR2 IFNA21 | Hepatitis C |
| KEGG:04217 | 0.0230797254414 | 0.5 | IFNAR2 IFNA21 | Necroptosis |
| KEGG:05164 | 0.0254912281659 | 0.5 | IFNAR2 IFNA21 | Influenza A |
| KEGG:04621 | 0.02620193588 | 0.5 | IFNAR2 IFNA21 | NOD-like receptor signaling pathway |
| KEGG:05167 | 0.0346546128597 | 0.5 | IFNAR2 IFNA21 | Kaposi sarcoma-associated herpesvirus infection |
| KEGG:05169 | 0.0397541089323 | 0.5 | IFNAR2 IFNA21 | Epstein-Barr virus infection |
| KEGG:04060 | 0.0475663770677 | 0.5 | IFNAR2 IFNA21 | Cytokine-cytokine receptor interaction |
| CORUM:7046 | 0.049938562206 | 0.25 | IFNAR2 | IFNAR2-IFNA2 complex |
| CORUM:7047 | 0.049938562206 | 0.25 | IFNAR2 | IFNAR1-IFNAR2-IFNA2 complex |
| CORUM:7045 | 0.049938562206 | 0.25 | IFNAR2 | IFNAR1-IFNAR2-IFNW1 complex |
| CORUM:552 | 0.049938562206 | 0.25 | IFNAR2 | IFNAR1-IFNAR2-IFNB1 complex |
| KEGG:05171 | 0.049994875911 | 0.5 | IFNAR2 IFNA21 | Coronavirus disease - COVID-19 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IFI44 | IFNA21 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IFNAR2 | IFNA21 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IFI44L | IFNA21 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IFNAR2 | IFI44 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| IFNAR2 | IFI44L | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| IFI44 | IFI44L | 0.572 | 0.378 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes