hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12028.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AKR7A2 | Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase) | 5 | UniProt NCBI |
| ACAT1 | Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2) | 5 | UniProt NCBI |
| PNISR | Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18) | 5 | UniProt NCBI |
| AKR7L | Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) | 5 | UniProt NCBI |
| AKR7A3 | Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP699 | 2.37821910987e-05 | 0.666666666667 | AKR7A2 AKR7A3 | Aflatoxin B1 metabolism |
| REAC:R-HSA-5423646 | 0.000926675585137 | 0.666666666667 | AKR7A2 AKR7A3 | Aflatoxin activation and detoxification |
| KEGG:00980 | 0.00130273084965 | 0.666666666667 | AKR7A2 AKR7A3 | Metabolism of xenobiotics by cytochrome P450 |
| WP:WP702 | 0.0101834993772 | 0.666666666667 | AKR7A2 AKR7A3 | Metapathway biotransformation Phase I and II |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AKR7A2 | AKR7A3 | 0.999 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| AKR7A3 | AKR7L | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AKR7A2 | AKR7L | 0.987 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AKR7A2 | ACAT1 | 0.862 | 0.054 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| AKR7L | PNISR | 0.833 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AKR7L | ACAT1 | 0.128 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AKR7A3 | ACAT1 | 0.05 | 0.102 | bioplex3_HEK293 bioplex () bioplex3_WMM |
| ACAT1 | PNISR | 0.015 | 0.054 | gupta_WMM WMM_only boldt_WMM |
Related Complexes