hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12031.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SNAPC2 | snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE-binding factor subunit delta) (PTF subunit delta) (Small nuclear RNA-activating complex polypeptide 2) (snRNA-activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) | 5 | UniProt NCBI |
| ZNF594 | Zinc finger protein 594 (Zinc finger protein HZF18) | 3 | UniProt NCBI |
| CCDC66 | Coiled-coil domain-containing protein 66 | 5 | UniProt NCBI |
| ANKRD36B | Ankyrin repeat domain-containing protein 36B (CLL-associated antigen KW-1) | 5 | UniProt NCBI |
| VLDLR | Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) | 5 | UniProt NCBI |
| SNAPC1 | snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) | 5 | UniProt NCBI |
| SNAPC3 | snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit) | 5 | UniProt NCBI |
| CHD7 | Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) | 5 | UniProt NCBI |
| RASA1 | Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) | 5 | UniProt NCBI |
| ZNF107 | Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25) | 4 | UniProt NCBI |
| SNAPC5 | snRNA-activating protein complex subunit 5 (SNAPc subunit 5) (Small nuclear RNA-activating complex polypeptide 5) (snRNA-activating protein complex 19 kDa subunit) (SNAPc 19 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:114 | 4.03199797571e-11 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | SNAPc (small nuclear RNA-activating protein) complex |
| REAC:R-HSA-76071 | 4.64950515139e-07 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| REAC:R-HSA-76046 | 1.22580923685e-06 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | RNA Polymerase III Transcription Initiation |
| REAC:R-HSA-749476 | 2.17048260795e-06 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | RNA Polymerase III Abortive And Retractive Initiation |
| REAC:R-HSA-74158 | 2.17048260795e-06 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | RNA Polymerase III Transcription |
| GO:0009301 | 1.30949840786e-05 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | snRNA transcription |
| REAC:R-HSA-6807505 | 2.68548303177e-05 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | RNA polymerase II transcribes snRNA genes |
| GO:0042796 | 0.00040312426486 | 0.3 | SNAPC3 SNAPC1 SNAPC5 | snRNA transcription by RNA polymerase III |
| GO:0140223 | 0.00105973484827 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | general transcription initiation factor activity |
| GO:0006383 | 0.00105973484827 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | transcription by RNA polymerase III |
| GO:0016073 | 0.0014725005364 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | snRNA metabolic process |
| GO:0000995 | 0.00252937426606 | 0.3 | SNAPC3 SNAPC1 SNAPC5 | RNA polymerase III general transcription initiation factor activity |
| GO:0042795 | 0.00418195709292 | 0.3 | SNAPC3 SNAPC1 SNAPC5 | snRNA transcription by RNA polymerase II |
| GO:0098781 | 0.0255498654968 | 0.4 | SNAPC2 SNAPC1 SNAPC5 SNAPC3 | ncRNA transcription |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SNAPC2 | SNAPC1 | 0.999 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SNAPC1 | SNAPC3 | 0.998 | 0.178 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| SNAPC5 | SNAPC1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ANKRD36B | RASA1 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ANKRD36B | VLDLR | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CCDC66 | ANKRD36B | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ANKRD36B | SNAPC2 | 0.974 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ZNF594 | ANKRD36B | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHD7 | ANKRD36B | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SNAPC2 | SNAPC3 | 0.96 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only |
| ANKRD36B | SNAPC1 | 0.945 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SNAPC5 | SNAPC2 | 0.909 | bioplex_WMM bioplex3_WMM WMM_only | |
| SNAPC5 | SNAPC3 | 0.891 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANKRD36B | SNAPC3 | 0.881 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ANKRD36B | ZNF107 | 0.83 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CCDC66 | SNAPC2 | 0.415 | 0.064 | bioplex3_WMM WMM_only |
| ZNF594 | ZNF107 | 0.391 | bioplex3_WMM WMM_only | |
| ZNF594 | CCDC66 | 0.278 | bioplex3_WMM WMM_only | |
| CCDC66 | SNAPC3 | 0.25 | 0.098 | bioplex3_WMM WMM_only |
| CCDC66 | RASA1 | 0.214 | 0.052 | bioplex3_WMM WMM_only |
| RASA1 | SNAPC3 | 0.214 | 0.072 | bioplex3_WMM WMM_only |
| CHD7 | RASA1 | 0.214 | 0.046 | bioplex3_WMM WMM_only |
| RASA1 | SNAPC2 | 0.214 | 0.136 | bioplex3_WMM WMM_only |
| ZNF594 | RASA1 | 0.214 | bioplex3_WMM WMM_only | |
| VLDLR | RASA1 | 0.146 | 0.092 | bioplex3_WMM WMM_only |
| RASA1 | SNAPC1 | 0.146 | 0.076 | bioplex3_WMM WMM_only |
| CHD7 | CCDC66 | 0.132 | 0.118 | bioplex3_WMM youn_WMM WMM_only |
| ZNF594 | SNAPC2 | 0.113 | bioplex3_WMM WMM_only | |
| CCDC66 | VLDLR | 0.113 | 0.068 | bioplex3_WMM WMM_only |
| SNAPC1 | ZNF107 | 0.11 | bioplex3_WMM WMM_only | |
| VLDLR | SNAPC1 | 0.102 | 0.122 | bioplex3_WMM WMM_only |
| CCDC66 | SNAPC1 | 0.099 | 0.17 | bioplex3_WMM youn_WMM WMM_only |
| SNAPC3 | ZNF107 | 0.097 | bioplex3_WMM WMM_only | |
| CHD7 | ZNF594 | 0.095 | bioplex3_WMM WMM_only | |
| CHD7 | SNAPC2 | 0.095 | 0.046 | bioplex3_WMM WMM_only |
| VLDLR | SNAPC3 | 0.089 | 0.092 | bioplex3_WMM WMM_only |
| SNAPC2 | ZNF107 | 0.089 | bioplex3_WMM WMM_only | |
| ZNF594 | SNAPC3 | 0.078 | bioplex3_WMM WMM_only | |
| VLDLR | SNAPC2 | 0.078 | 0.08 | bioplex3_WMM WMM_only |
| CHD7 | ZNF107 | 0.077 | bioplex3_WMM youn_WMM WMM_only | |
| CHD7 | SNAPC1 | 0.077 | 0.098 | bioplex3_WMM youn_WMM WMM_only |
| CHD7 | VLDLR | 0.076 | 0.092 | bioplex3_WMM WMM_only |
| ZNF594 | VLDLR | 0.076 | bioplex3_WMM WMM_only | |
| ZNF594 | SNAPC1 | 0.076 | bioplex3_WMM WMM_only | |
| CCDC66 | ZNF107 | 0.076 | bioplex3_WMM WMM_only | |
| VLDLR | ZNF107 | 0.076 | bioplex3_WMM WMM_only | |
| CHD7 | SNAPC3 | 0.071 | 0.14 | bioplex3_WMM WMM_only |
| RASA1 | ZNF107 | 0.055 | bioplex3_WMM WMM_only |
Related Complexes