hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12041.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EEF1D | Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | 5 | UniProt NCBI |
| EEF1A1 | Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) | 5 | UniProt NCBI |
| EEF1A2 | Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) | 5 | UniProt NCBI |
| KMT5B | Histone-lysine N-methyltransferase KMT5B (Lysine N-methyltransferase 5B) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361) | 5 | UniProt NCBI |
| ABTB1 | Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein) | 5 | UniProt NCBI |
| TTLL12 | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) | 5 | UniProt NCBI |
| VARS1 | Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) | 5 | UniProt NCBI |
| ATF4 | Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67) | 5 | UniProt NCBI |
| CEBPG | CCAAT/enhancer-binding protein gamma (C/EBP gamma) | 5 | UniProt NCBI |
| EEF1AKMT1 | EEF1A lysine methyltransferase 1 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2) (Protein-lysine N-methyltransferase N6AMT2) (eEF1A-KMT) | 4 | UniProt NCBI |
| EEF1B2 | Elongation factor 1-beta (EF-1-beta) | 5 | UniProt NCBI |
| CARS1 | Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) | 5 | UniProt NCBI |
| MLLT10 | Protein AF-10 (ALL1-fused gene from chromosome 10 protein) | 5 | UniProt NCBI |
| MLLT6 | Protein AF-17 (ALL1-fused gene from chromosome 17 protein) | 5 | UniProt NCBI |
| EEF1G | Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) | 5 | UniProt NCBI |
| PBDC1 | Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1) | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP107 | 0.000891130047212 | 0.25 | EEF1B2 EEF1A1 EEF1A2 | Translation factors |
| GO:0003746 | 0.00463290208809 | 0.25 | EEF1B2 EEF1A1 EEF1A2 | translation elongation factor activity |
| REAC:R-HSA-156842 | 0.0138503617857 | 0.25 | EEF1B2 EEF1A1 EEF1A2 | Eukaryotic Translation Elongation |
| REAC:R-HSA-72766 | 0.0175344308275 | 0.333333333333 | EEF1B2 CARS1 EEF1A1 EEF1A2 | Translation |
| REAC:R-HSA-8876725 | 0.0200246560632 | 0.166666666667 | EEF1AKMT1 EEF1A1 | Protein methylation |
| KEGG:05134 | 0.0354809408111 | 0.166666666667 | EEF1A1 EEF1A2 | Legionellosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| EEF1D | EEF1B2 | 1.0 | |
| EEF1B2 | EEF1G | 1.0 | 0.842 |
| EEF1D | EEF1G | 1.0 | |
| EEF1A1 | EEF1B2 | 1.0 | 0.846 |
| EEF1D | EEF1A2 | 1.0 | |
| EEF1D | VARS1 | 1.0 | |
| EEF1A1 | EEF1G | 1.0 | 0.578 |
| EEF1A1 | PBDC1 | 1.0 | 0.133428571429 |
| EEF1D | EEF1A1 | 1.0 | |
| EEF1D | CARS1 | 1.0 | |
| EEF1D | ABTB1 | 0.999 | |
| EEF1A1 | VARS1 | 0.999 | 0.522 |
| EEF1A2 | EEF1B2 | 0.999 | 0.534 |
| VARS1 | EEF1B2 | 0.999 | 0.354 |
| MLLT6 | MLLT10 | 0.999 | 0.122 |
| EEF1A1 | EEF1A2 | 0.999 | 0.964 |
| VARS1 | EEF1G | 0.999 | 0.532 |
| EEF1A2 | EEF1G | 0.999 | 0.344181818182 |
| VARS1 | ABTB1 | 0.999 | |
| TTLL12 | PBDC1 | 0.999 | 0.052 |
| EEF1A2 | VARS1 | 0.999 | 0.362 |
| EEF1A2 | PBDC1 | 0.999 | 0.112 |
| VARS1 | CARS1 | 0.999 | 0.454 |
| EEF1B2 | ABTB1 | 0.999 | |
| ABTB1 | EEF1G | 0.999 | |
| EEF1A2 | CARS1 | 0.998 | 0.252 |
| EEF1D | MLLT6 | 0.997 | |
| EEF1A1 | CARS1 | 0.996 | 0.258 |
| EEF1A1 | TTLL12 | 0.995 | 0.28 |
| EEF1A2 | ABTB1 | 0.995 | |
| EEF1A1 | EEF1AKMT1 | 0.994 | 0.24 |
| MLLT6 | CEBPG | 0.994 | |
| EEF1A2 | TTLL12 | 0.993 | 0.276 |
| EEF1B2 | MLLT6 | 0.992 | 0.064 |
| VARS1 | MLLT6 | 0.99 | 0.117816531165 |
| CARS1 | ABTB1 | 0.986 | |
| CARS1 | MLLT6 | 0.985 | 0.052 |
| ATF4 | CEBPG | 0.981 | |
| EEF1D | MLLT10 | 0.978 | |
| EEF1A1 | ABTB1 | 0.978 | |
| EEF1A2 | EEF1AKMT1 | 0.973 | 0.156 |
| CARS1 | EEF1B2 | 0.955 | 0.174 |
| EEF1G | MLLT6 | 0.948 | 0.1 |
| TTLL12 | EEF1AKMT1 | 0.944 | 0.064 |
| EEF1D | CEBPG | 0.944 | |
| CARS1 | EEF1G | 0.943 | 0.244 |
| CARS1 | KMT5B | 0.938 | |
| VARS1 | CEBPG | 0.932 | |
| EEF1A1 | MLLT6 | 0.93 | 0.398 |
| EEF1G | CEBPG | 0.851 | |
| EEF1B2 | CEBPG | 0.724 | |
| EEF1A1 | MLLT10 | 0.721 | 0.278 |
| CARS1 | MLLT10 | 0.711 | 0.074 |
| EEF1A2 | MLLT10 | 0.648 | 0.236 |
| EEF1A2 | MLLT6 | 0.611 | 0.370275 |
| ABTB1 | MLLT10 | 0.418 | |
| EEF1G | MLLT10 | 0.403 | 0.104 |
| CARS1 | CEBPG | 0.299 | |
| VARS1 | MLLT10 | 0.292 | 0.104 |
| EEF1B2 | MLLT10 | 0.184 | 0.106 |
| MLLT10 | CEBPG | 0.164 | |
| EEF1A2 | CEBPG | 0.13 | |
| VARS1 | ATF4 | 0.102 | |
| TTLL12 | VARS1 | 0.099 | 0.33 |
| TTLL12 | CARS1 | 0.092 | 0.168 |
| EEF1D | ATF4 | 0.073 | |
| EEF1A1 | CEBPG | 0.057 | |
| VARS1 | PBDC1 | 0.044 | 0.114 |
| CARS1 | PBDC1 | 0.043 | 0.114 |
| EEF1B2 | PBDC1 | 0.041 | 0.08 |
| TTLL12 | ABTB1 | 0.04 | |
| PBDC1 | ATF4 | 0.038 | |
| EEF1D | TTLL12 | 0.032 | |
| EEF1G | PBDC1 | 0.023 | 0.169666666667 |
| EEF1A1 | ATF4 | 0.021 | |
| EEF1B2 | ATF4 | 0.016 | |
| EEF1A1 | KMT5B | 0.015 | |
| EEF1G | KMT5B | 0.013 | |
| PBDC1 | CEBPG | 0.013 | |
| EEF1D | PBDC1 | 0.012 | |
| ABTB1 | PBDC1 | 0.01 | |
| TTLL12 | MLLT6 | 0.01 | 0.146 |
| TTLL12 | EEF1G | 0.01 | 0.181333333333 |
| TTLL12 | EEF1B2 | 0.009 | 0.11 |
| EEF1B2 | KMT5B | 0.007 | |
| EEF1G | ATF4 | 0.006 | |
| VARS1 | EEF1AKMT1 | 0.004 | 0.12 |
| EEF1D | EEF1AKMT1 | 0.003 | |
| EEF1AKMT1 | EEF1B2 | 0.001 | 0.12 |
| EEF1AKMT1 | EEF1G | 0.001 | 0.12 |
Related Complexes