hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12046.1
Complex Portal: CPX-11471
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDHB9 | Protocadherin beta-9 (PCDH-beta-9) (Protocadherin-3H) | 4 | UniProt NCBI |
| PCDHB13 | Protocadherin beta-13 (PCDH-beta-13) | 4 | UniProt NCBI |
| TMTC2 | Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 2) (Transmembrane and tetratricopeptide repeat-containing 2) | 5 | UniProt NCBI |
| TMEM97 | Sigma intracellular receptor 2 (S2R) (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (MAC30) (Transmembrane protein 97) | 5 | UniProt NCBI |
| PCDHB8 | Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I) | 4 | UniProt NCBI |
| PCDHB2 | Protocadherin beta-2 (PCDH-beta-2) | 4 | UniProt NCBI |
| PCDHB5 | Protocadherin beta-5 (PCDH-beta-5) | 4 | UniProt NCBI |
| MYRF | Myelin regulatory factor (EC 3.4.-.-) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal] | 5 | UniProt NCBI |
| B3GNT4 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4) | 5 | UniProt NCBI |
| PCDHB10 | Protocadherin beta-10 (PCDH-beta-10) | 4 | UniProt NCBI |
| PCDHB4 | Protocadherin beta-4 (PCDH-beta-4) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016339 | 1.87726203329e-09 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO:0007416 | 1.54242494298e-06 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | synapse assembly |
| GO:0098742 | 6.34754017446e-06 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | cell-cell adhesion via plasma-membrane adhesion molecules |
| GO:0050808 | 0.000242291982993 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | synapse organization |
| GO:0034329 | 0.000769089338526 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | cell junction assembly |
| GO:0007268 | 0.00396944759162 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | chemical synaptic transmission |
| GO:0098916 | 0.00396944759162 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | anterograde trans-synaptic signaling |
| GO:0099537 | 0.00424405167737 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | trans-synaptic signaling |
| GO:0099536 | 0.00595686034927 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | synaptic signaling |
| GO:0034330 | 0.0108039511372 | 0.545454545455 | PCDHB4 PCDHB9 PCDHB2 PCDHB10 PCDHB13 PCDHB5 | cell junction organization |
| TF:M01284_1 | 0.0221472630333 | 0.636363636364 | PCDHB8 PCDHB9 PCDHB2 PCDHB10 TMEM97 PCDHB13 PCDHB5 | Factor: Sox-9; motif: RNACAAAGGVN; match class: 1 |
| GO:0007155 | 0.0494189524924 | 0.636363636364 | PCDHB4 PCDHB8 PCDHB2 PCDHB9 PCDHB10 PCDHB13 PCDHB5 | cell adhesion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| PCDHB9 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB8 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB5 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB4 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB2 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB2 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB5 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB2 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB4 | PCDHB5 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB5 | PCDHB8 | 0.946 | 0.138 |
mutually_exclusive (Q9Y5E6)
|
| PCDHB4 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB9 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB4 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB4 | PCDHB13 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB13 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB13 | PCDHB10 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB13 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB2 | PCDHB4 | 0.933 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB13 | PCDHB5 | 0.931 | ||
| PCDHB2 | PCDHB13 | 0.923 |
mutually_exclusive (Q9Y5E6)
|
|
| TMTC2 | PCDHB8 | 0.904 | 0.068 | |
| PCDHB4 | MYRF | 0.904 | ||
| B3GNT4 | PCDHB4 | 0.904 | ||
| TMTC2 | PCDHB9 | 0.904 | ||
| B3GNT4 | PCDHB10 | 0.902 | ||
| B3GNT4 | PCDHB9 | 0.902 | ||
| PCDHB9 | MYRF | 0.902 | ||
| PCDHB8 | MYRF | 0.902 | ||
| B3GNT4 | PCDHB8 | 0.902 | ||
| PCDHB10 | TMEM97 | 0.899 | ||
| PCDHB10 | MYRF | 0.893 | ||
| PCDHB9 | TMEM97 | 0.892 | ||
| PCDHB8 | TMEM97 | 0.892 | 0.064 | |
| TMTC2 | PCDHB10 | 0.883 | ||
| PCDHB2 | PCDHB5 | 0.827 |
mutually_exclusive (Q9Y5E6)
|
|
| PCDHB2 | TMTC2 | 0.768 | ||
| PCDHB5 | MYRF | 0.768 | ||
| B3GNT4 | PCDHB5 | 0.768 | ||
| PCDHB4 | TMTC2 | 0.768 | ||
| PCDHB4 | TMEM97 | 0.73 | ||
| PCDHB2 | MYRF | 0.73 | ||
| PCDHB2 | B3GNT4 | 0.73 | ||
| TMTC2 | PCDHB5 | 0.715 | 0.08 | |
| B3GNT4 | PCDHB13 | 0.696 | ||
| PCDHB13 | MYRF | 0.688 | ||
| PCDHB5 | TMEM97 | 0.675 | 0.058 | |
| PCDHB2 | TMEM97 | 0.675 | ||
| PCDHB13 | TMEM97 | 0.675 | ||
| B3GNT4 | TMEM97 | 0.675 | ||
| TMEM97 | MYRF | 0.675 | ||
| TMTC2 | PCDHB13 | 0.668 | ||
| TMTC2 | TMEM97 | 0.652 | 0.028 | |
| B3GNT4 | MYRF | 0.418 | ||
| B3GNT4 | TMTC2 | 0.356 | ||
| TMTC2 | MYRF | 0.22 |
Related Complexes