hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12048.1
Complex Portal: CPX-24077
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] | 5 | UniProt NCBI |
| ARFGAP3 | ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3) | 5 | UniProt NCBI |
| SHB | SH2 domain-containing adapter protein B | 5 | UniProt NCBI |
| RAD54L | DNA repair and recombination protein RAD54-like (EC 3.6.4.12) (RAD54 homolog) (hHR54) (hRAD54) | 5 | UniProt NCBI |
| NTAQ1 | Protein N-terminal glutamine amidohydrolase (EC 3.5.1.122) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1) | 5 | UniProt NCBI |
| SBNO1 | Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) | 4 | UniProt NCBI |
| ZHX3 | Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RAD54L | NTAQ1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ERN1 | NTAQ1 | 0.997 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NTAQ1 | ZHX3 | 0.984 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NTAQ1 | ARFGAP3 | 0.981 | 0.236 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SHB | NTAQ1 | 0.978 | 0.236 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NTAQ1 | SBNO1 | 0.95 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM fraction | ||
| ERN1 | RAD54L | 0.611 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RAD54L | SBNO1 | 0.323 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SHB | ARFGAP3 | 0.265 | 0.092 |
mutually_exclusive (Q96HA8)
|
bioplex_WMM bioplex3_WMM WMM_only |
| SBNO1 | ARFGAP3 | 0.22 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | ||
| ERN1 | ARFGAP3 | 0.213 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | |
| SHB | ERN1 | 0.213 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| ERN1 | SBNO1 | 0.205 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ERN1 | ZHX3 | 0.187 | 0.256 | bioplex_WMM bioplex3_WMM WMM_only | |
| SHB | RAD54L | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RAD54L | ARFGAP3 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RAD54L | ZHX3 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SHB | ZHX3 | 0.164 | 0.118 | bioplex_WMM bioplex3_WMM WMM_only | |
| SHB | SBNO1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SBNO1 | ZHX3 | 0.074 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| ZHX3 | ARFGAP3 | 0.037 | 0.066 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes