hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12050.1
Complex Portal: CPX-11356
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INS | Insulin [Cleaved into: Insulin B chain; Insulin A chain] | 5 | UniProt NCBI |
| SEMA3G | Semaphorin-3G (Semaphorin sem2) | 4 | UniProt NCBI |
| MFAP5 | Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2) | 5 | UniProt NCBI |
| PRSS12 | Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP661 | 0.0124405187696 | 0.25 | INS | Glucose homeostasis |
| HP:0011104 | 0.0126114492305 | 0.5 | INS MFAP5 | Abnormality of blood volume homeostasis |
| HP:0011106 | 0.0126114492305 | 0.5 | INS MFAP5 | Hypovolemia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| INS | PRSS12 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SEMA3G | PRSS12 | 0.904 | bioplex3_WMM WMM_only | ||
| PRSS12 | MFAP5 | 0.85 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes