hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12054.1
Complex Portal: CPX-15264
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KRCC1 | Lysine-rich coiled-coil protein 1 (Cryptogenic hepatitis-binding protein 2) | 3 | UniProt NCBI |
| GLRX5 | Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) | 5 | UniProt NCBI |
| TBCB | Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) | 5 | UniProt NCBI |
| NFU1 | NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (HIRA-interacting protein 5) | 5 | UniProt NCBI |
| MRRF | Ribosome-recycling factor, mitochondrial (RRF) (mtRRF) (Ribosome-releasing factor, mitochondrial) | 5 | UniProt NCBI |
| NAT1 | Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Monomorphic arylamine N-acetyltransferase) (MNAT) (N-acetyltransferase type 1) (NAT-1) | 5 | UniProt NCBI |
| NDNF | Protein NDNF (Neuron-derived neurotrophic factor) | 5 | UniProt NCBI |
| MCEE | Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5152 | 0.00161645869838 | 0.285714285714 | GLRX5 NFU1 | Iron sulfur cluster biogenesis |
| HP:0033107 | 0.00636192078034 | 0.428571428571 | GLRX5 NFU1 MCEE | Abnormal circulating proteinogenic amino acid concentration |
| HP:0002154 | 0.0199339480346 | 0.285714285714 | GLRX5 NFU1 | Hyperglycinemia |
| HP:0010895 | 0.0254041861805 | 0.285714285714 | GLRX5 NFU1 | Abnormal circulating glycine concentration |
| HP:0003112 | 0.0292982733881 | 0.428571428571 | GLRX5 NFU1 MCEE | Abnormal circulating amino acid concentration |
| HP:0010894 | 0.0348446257606 | 0.285714285714 | GLRX5 NFU1 | Abnormal circulating serine family amino acid concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NFU1 | MRRF | 0.997 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GLRX5 | NAT1 | 0.906 | 0.034 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NFU1 | MCEE | 0.884 | 0.09 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GLRX5 | MRRF | 0.873 | 0.138 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM fraction | |
| NAT1 | NFU1 | 0.869 | 0.042 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NAT1 | MRRF | 0.861 | 0.036 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NFU1 | KRCC1 | 0.841 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NFU1 | NDNF | 0.83 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NAT1 | TBCB | 0.811 | 0.044 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GLRX5 | MCEE | 0.114 | 0.036 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| NFU1 | TBCB | 0.077 | 0.026 | bioplex_WMM bioplex3_WMM WMM_only | |
| MRRF | TBCB | 0.064 | 0.0480153846154 | bioplex3_WMM WMM_only | |
| GLRX5 | NFU1 | 0.043 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only | |
| GLRX5 | TBCB | 0.016 | 0.022 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| KRCC1 | TBCB | 0.013 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MCEE | TBCB | 0.009 | 0.05 | fraction | |
| NDNF | TBCB | 0.006 | gupta_WMM WMM_only |
Related Complexes