hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12090.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
RPP40	Ribonuclease P protein subunit p40 (RNaseP protein p40) (RNase P subunit 1)	5	UniProt NCBI
IBTK	Inhibitor of Bruton tyrosine kinase (IBtk)	5	UniProt NCBI
UBE2NL	Putative ubiquitin-conjugating enzyme E2 N-like (Epididymis tissue protein Li 174)	2	UniProt NCBI
RPP14	Ribonuclease P protein subunit p14	5	UniProt NCBI
POP7	Ribonuclease P protein subunit p20 (RNaseP protein p20) (Ribonucleases P/MRP protein subunit POP7 homolog) (hPOP7)	5	UniProt NCBI
ENOX1	Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]	5	UniProt NCBI
RPP21	Ribonuclease P protein subunit p21 (RNaseP protein p21) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V)	5	UniProt NCBI
POP5	Ribonuclease P/MRP protein subunit POP5 (hPop5)	5	UniProt NCBI
C18orf21	UPF0711 protein C18orf21 (HBV X-transactivated gene 13 protein) (HBV XAg-transactivated protein 13)	2	UniProt NCBI
POP4	Ribonuclease P protein subunit p29 (hPOP4)	5	UniProt NCBI
ENOX2	Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]	5	UniProt NCBI
RPP30	Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2)	5	UniProt NCBI
RPP25	Ribonuclease P protein subunit p25 (RNase P protein subunit p25)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:123	2.62824948129e-23	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	Rnase/Mrp complex
GO:0030681	2.16042107362e-20	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	multimeric ribonuclease P complex
GO:0033204	2.16042107362e-20	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ribonuclease P RNA binding
GO:0004526	7.91961549209e-20	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ribonuclease P activity
GO:0030677	6.17429254461e-19	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ribonuclease P complex
GO:0001682	6.17429254461e-19	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA 5'-leader removal
GO:0004549	1.44031747814e-18	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA-specific ribonuclease activity
GO:0099116	3.08564305873e-18	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA 5'-end processing
GO:0034471	6.0330281726e-17	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ncRNA 5'-end processing
GO:0000966	9.74328699063e-17	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	RNA 5'-end processing
GO:0016891	7.47120768672e-16	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	RNA endonuclease activity, producing 5'-phosphomonoesters
REAC:R-HSA-6784531	3.1422180212e-15	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA processing in the nucleus
GO:1902555	3.76799997089e-15	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	endoribonuclease complex
GO:0016893	6.6284473992e-15	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:1905348	1.12307793378e-14	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	endonuclease complex
GO:0000172	9.56047657747e-14	0.5	RPP30 POP5 RPP40 POP4 RPP25 POP7	ribonuclease MRP complex
REAC:R-HSA-72306	4.37098104851e-13	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA processing
GO:0004521	5.78168115902e-13	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	RNA endonuclease activity
GO:0004519	3.02771250521e-11	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	endonuclease activity
GO:0004540	1.02943935027e-10	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	RNA nuclease activity
GO:0140101	1.78035658329e-10	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	catalytic activity, acting on a tRNA
GO:0008033	2.39570660664e-10	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA processing
GO:0005732	2.5350951953e-10	0.5	RPP30 POP5 RPP40 POP4 RPP25 POP7	sno(s)RNA-containing ribonucleoprotein complex
KEGG:03008	5.90509026779e-10	0.5	RPP30 POP5 RPP40 POP4 RPP25 POP7	Ribosome biogenesis in eukaryotes
GO:0004518	4.12683615995e-09	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	nuclease activity
GO:0006399	9.81787949133e-09	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	tRNA metabolic process
GO:0140098	1.00430049224e-06	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	catalytic activity, acting on RNA
GO:0034470	2.32781074424e-06	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ncRNA processing
REAC:R-HSA-8953854	2.51700385471e-06	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	Metabolism of RNA
GO:0140640	3.53968525939e-05	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	catalytic activity, acting on a nucleic acid
GO:0034660	4.84890632588e-05	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ncRNA metabolic process
REAC:R-HSA-6791226	5.37942108178e-05	0.416666666667	RPP30 RPP25 RPP40 RPP21 RPP14	Major pathway of rRNA processing in the nucleolus and cytosol
REAC:R-HSA-8868773	7.04178455902e-05	0.416666666667	RPP30 RPP25 RPP40 RPP21 RPP14	rRNA processing in the nucleus and cytosol
GO:0005655	8.45465618902e-05	0.25	RPP30 RPP40 RPP21	nucleolar ribonuclease P complex
REAC:R-HSA-72312	9.08815072864e-05	0.416666666667	RPP30 RPP25 RPP40 RPP21 RPP14	rRNA processing
GO:0016788	0.00010693084924	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	hydrolase activity, acting on ester bonds
GO:1990904	0.000148299709923	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	ribonucleoprotein complex
GO:0006396	0.00113865950967	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	RNA processing
GO:0140535	0.00197746749114	0.666666666667	RPP21 POP5 RPP14 RPP25 POP7 RPP30 POP4 RPP40	intracellular protein-containing complex
GO:0005730	0.0399194418328	0.583333333333	RPP21 POP5 RPP14 POP7 RPP30 POP4 RPP40	nucleolus

Edges

Protein 1	Protein 2	Score	ProteomeHD
POP7	POP4	1.0	0.192
RPP30	RPP14	1.0	0.568
RPP40	C18orf21	1.0	0.114
POP7	C18orf21	1.0	0.134
POP5	C18orf21	1.0	0.236
RPP30	RPP25	1.0	0.252909090909
RPP30	POP4	1.0	0.826
POP4	RPP25	1.0	0.204
POP5	RPP25	1.0	0.128
POP7	RPP21	1.0	0.194
POP5	RPP30	0.999	0.312
RPP14	C18orf21	0.999	0.112
RPP40	POP4	0.999	0.512
POP7	RPP25	0.999	0.132
RPP40	RPP21	0.999	0.186
POP5	POP4	0.999	0.342
POP5	RPP21	0.999	0.222
RPP30	POP7	0.999	0.298
POP5	POP7	0.999	0.318
POP5	RPP14	0.999	0.312
RPP40	RPP25	0.999	0.05
RPP21	POP4	0.999	0.14
POP5	RPP40	0.999	0.22
RPP14	RPP21	0.999	0.178
RPP40	RPP14	0.999	0.756
RPP21	RPP25	0.999	0.054
RPP30	C18orf21	0.999	0.342
RPP14	POP7	0.999	0.396
RPP14	POP4	0.999	0.31
RPP30	RPP21	0.999	0.336
RPP30	RPP40	0.999	0.626
C18orf21	RPP25	0.999	0.12
RPP14	RPP25	0.999	0.116
RPP40	POP7	0.998	0.164
C18orf21	POP4	0.998	0.206
IBTK	POP7	0.998	0.066
POP5	ENOX2	0.996
POP5	ENOX1	0.995	0.104
RPP30	ENOX2	0.989
RPP14	UBE2NL	0.938
ENOX1	ENOX2	0.853
RPP21	C18orf21	0.822	0.224
IBTK	C18orf21	0.82	0.052
POP5	IBTK	0.82	0.068
ENOX2	POP4	0.811
ENOX2	RPP40	0.811
ENOX2	POP7	0.811
ENOX2	RPP25	0.797
ENOX2	C18orf21	0.79
ENOX2	RPP14	0.79
ENOX1	RPP21	0.768	0.092
IBTK	RPP14	0.726	0.064
ENOX1	C18orf21	0.553	0.11
ENOX1	RPP14	0.553	0.07
ENOX1	RPP30	0.488	0.104
ENOX1	RPP25	0.454	0.086
ENOX1	RPP40	0.44	0.056
ENOX1	POP7	0.44	0.072
ENOX1	POP4	0.407	0.148
ENOX2	RPP21	0.337
IBTK	RPP25	0.334	0.084
RPP30	IBTK	0.29	0.096
C18orf21	UBE2NL	0.25
POP5	UBE2NL	0.25
IBTK	POP4	0.247	0.12
RPP40	IBTK	0.243	0.038
ENOX1	IBTK	0.21	0.068
ENOX2	IBTK	0.113
RPP25	UBE2NL	0.113
RPP40	UBE2NL	0.031
RPP30	UBE2NL	0.025
POP7	UBE2NL	0.025
POP4	UBE2NL	0.019
IBTK	UBE2NL	0.007

Related Complexes

Genename	Complexes
RPP40	huMAP3_00441.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
IBTK	huMAP3_00441.1 huMAP3_01276.1 huMAP3_05834.1 huMAP3_08346.1 huMAP3_08469.1 huMAP3_09863.1 huMAP3_11246.1 huMAP3_12090.1 huMAP3_13175.1
UBE2NL	huMAP3_12090.1
RPP14	huMAP3_00441.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
POP7	huMAP3_00441.1 huMAP3_04577.1 huMAP3_05834.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
ENOX1	huMAP3_00258.1 huMAP3_04158.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
RPP21	huMAP3_00441.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
POP5	huMAP3_00258.1 huMAP3_04158.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
C18orf21	huMAP3_00441.1 huMAP3_01364.1 huMAP3_06166.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_08971.1 huMAP3_10504.1 huMAP3_12090.1
POP4	huMAP3_00441.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
ENOX2	huMAP3_00258.1 huMAP3_04158.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1
RPP30	huMAP3_00258.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1 huMAP3_12301.1 huMAP3_12727.1
RPP25	huMAP3_00441.1 huMAP3_06709.1 huMAP3_08418.1 huMAP3_08469.1 huMAP3_12090.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_12090.1