hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12116.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MUC7 | Mucin-7 (MUC-7) (Apo-MG2) (Salivary mucin-7) | 5 | UniProt NCBI |
| HID1 | Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog) | 5 | UniProt NCBI |
| CRYGN | Gamma-crystallin N (Gamma-N-crystallin) | 3 | UniProt NCBI |
| RCAN2 | Calcipressin-2 (Down syndrome candidate region 1-like 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2) (Regulator of calcineurin 2) (Thyroid hormone-responsive protein ZAKI-4) | 4 | UniProt NCBI |
| CST2 | Cystatin-SA (Cystatin-2) (Cystatin-S5) | 5 | UniProt NCBI |
| CRH | Corticoliberin (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone) | 5 | UniProt NCBI |
| CA6 | Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase) | 5 | UniProt NCBI |
| CST5 | Cystatin-D (Cystatin-5) | 5 | UniProt NCBI |
| AKNAD1 | Protein AKNAD1 | 3 | UniProt NCBI |
| RNF141 | RING finger protein 141 (Zinc finger protein 230) | 5 | UniProt NCBI |
| PLEKHG6 | Pleckstrin homology domain-containing family G member 6 (PH domain-containing family G member 6) (Myosin-interacting guanine nucleotide exchange factor) (MyoGEF) | 5 | UniProt NCBI |
| AMY1C | Alpha-amylase 1C (EC 3.2.1.1) | 5 | UniProt NCBI |
| ZNF491 | Zinc finger protein 491 | 4 | UniProt NCBI |
| CST4 | Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1) | 5 | UniProt NCBI |
| CST1 | Cystatin-SN (Cystain-SA-I) (Cystatin-1) (Salivary cystatin-SA-1) | 5 | UniProt NCBI |
| ABCA8 | ABC-type organic anion transporter ABCA8 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 8) | 5 | UniProt NCBI |
| C10orf53 | UPF0728 protein C10orf53 | 2 | UniProt NCBI |
| HBQ1 | Hemoglobin subunit theta-1 (Hemoglobin theta-1 chain) (Theta-1-globin) | 4 | UniProt NCBI |
| BPIFA2 | BPI fold-containing family A member 2 (Parotid secretory protein) (PSP) (Short palate, lung and nasal epithelium carcinoma-associated protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04970 | 6.62368213865e-07 | 0.277777777778 | AMY1C CST4 CST1 MUC7 CST2 | Salivary secretion |
| GO:0001580 | 0.000243749587868 | 0.222222222222 | CST4 CST1 CST2 CA6 | detection of chemical stimulus involved in sensory perception of bitter taste |
| GO:0050913 | 0.000243749587868 | 0.222222222222 | CST4 CST1 CST2 CA6 | sensory perception of bitter taste |
| GO:0050912 | 0.000308512724491 | 0.222222222222 | CST4 CST1 CST2 CA6 | detection of chemical stimulus involved in sensory perception of taste |
| GO:0050909 | 0.00100226083111 | 0.222222222222 | CST4 CST1 CST2 CA6 | sensory perception of taste |
| GO:0050907 | 0.00411677761306 | 0.222222222222 | CST4 CST1 CST2 CA6 | detection of chemical stimulus involved in sensory perception |
| TF:M05310_1 | 0.0171362685288 | 0.166666666667 | CST4 CST2 CST1 | Factor: ZNF688; motif: MTCAKAAGACC; match class: 1 |
| GO:0050906 | 0.0245050571718 | 0.222222222222 | CST4 CST1 CST2 CA6 | detection of stimulus involved in sensory perception |
| GO:0009593 | 0.0284162007118 | 0.222222222222 | CST4 CST1 CST2 CA6 | detection of chemical stimulus |
| GO:0007606 | 0.0402197484158 | 0.222222222222 | CST4 CST1 CST2 CA6 | sensory perception of chemical stimulus |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| CST1 | CST4 | 1.0 | |
| HBQ1 | HID1 | 1.0 | |
| CRYGN | CA6 | 0.996 | |
| CA6 | C10orf53 | 0.993 | |
| CA6 | AKNAD1 | 0.992 | |
| MUC7 | C10orf53 | 0.992 | |
| BPIFA2 | AKNAD1 | 0.992 | |
| CST5 | AKNAD1 | 0.992 | |
| MUC7 | AMY1C | 0.99 | |
| CRH | CST5 | 0.99 | |
| CRH | BPIFA2 | 0.99 | |
| CST1 | MUC7 | 0.987 | |
| CA6 | ZNF491 | 0.987 | |
| HBQ1 | CA6 | 0.985 | |
| C10orf53 | AMY1C | 0.982 | |
| CST1 | BPIFA2 | 0.979 | |
| MUC7 | CST4 | 0.978 | |
| MUC7 | ZNF491 | 0.978 | |
| CST2 | C10orf53 | 0.977 | |
| AMY1C | AKNAD1 | 0.976 | |
| MUC7 | CST2 | 0.975 | |
| CST2 | BPIFA2 | 0.975 | |
| CST2 | AKNAD1 | 0.974 | |
| ABCA8 | CST2 | 0.974 | |
| BPIFA2 | AMY1C | 0.974 | |
| PLEKHG6 | CST1 | 0.97 | |
| CST2 | ZNF491 | 0.97 | |
| CRYGN | CST2 | 0.967 | |
| CST2 | AMY1C | 0.966 | |
| HBQ1 | MUC7 | 0.964 | |
| CST1 | RNF141 | 0.963 | |
| CST1 | AKNAD1 | 0.963 | |
| CST1 | CRYGN | 0.963 | |
| CST1 | C10orf53 | 0.963 | |
| CST4 | AKNAD1 | 0.96 | |
| PLEKHG6 | BPIFA2 | 0.96 | |
| ZNF491 | BPIFA2 | 0.96 | |
| C10orf53 | CST4 | 0.959 | |
| RNF141 | CST4 | 0.958 | |
| CRYGN | CST4 | 0.957 | |
| CST5 | AMY1C | 0.955 | |
| CRH | CST1 | 0.954 | |
| CST4 | BPIFA2 | 0.952 | |
| CRH | CST4 | 0.95 | |
| ABCA8 | CST4 | 0.95 | |
| CST2 | CST5 | 0.948 | |
| CST1 | CST5 | 0.944 | |
| CST2 | CST4 | 0.944 | |
| CST5 | BPIFA2 | 0.94 | |
| MUC7 | BPIFA2 | 0.932 | |
| CST5 | ZNF491 | 0.924 | |
| CST5 | CST4 | 0.919 | |
| CST1 | CST2 | 0.918 | |
| HBQ1 | CST2 | 0.915 | |
| CST1 | AMY1C | 0.915 | |
| MUC7 | RCAN2 | 0.914 | |
| CST1 | HBQ1 | 0.907 | |
| CST4 | AMY1C | 0.897 | |
| CA6 | AMY1C | 0.892 | |
| MUC7 | CA6 | 0.888 | |
| CA6 | BPIFA2 | 0.886 | |
| PLEKHG6 | CST5 | 0.877 | |
| CST2 | CA6 | 0.839 | |
| CST5 | CA6 | 0.833 | |
| HBQ1 | CST4 | 0.832 | |
| HBQ1 | BPIFA2 | 0.83 | |
| RCAN2 | AMY1C | 0.823 | |
| CST1 | CA6 | 0.802 | |
| HBQ1 | CST5 | 0.801 | |
| CA6 | CST4 | 0.778 | |
| CST2 | RCAN2 | 0.74 | |
| PLEKHG6 | AMY1C | 0.689 | |
| HBQ1 | AMY1C | 0.68 | |
| MUC7 | CST5 | 0.672 | |
| CST1 | RCAN2 | 0.621 | |
| PLEKHG6 | CST4 | 0.494 | |
| ZNF491 | CST4 | 0.425 | |
| RCAN2 | CST4 | 0.399 | |
| ZNF491 | AMY1C | 0.221 | |
| HID1 | CST2 | 0.113 | |
| HID1 | CA6 | 0.078 | |
| HID1 | BPIFA2 | 0.076 | |
| HID1 | CST5 | 0.076 | |
| HID1 | MUC7 | 0.076 | |
| HID1 | AMY1C | 0.076 | |
| CST1 | HID1 | 0.064 | |
| HID1 | CST4 | 0.055 | |
| ABCA8 | AMY1C | 0.034 |
Related Complexes