hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12122.1
Complex Portal: CPX-22586
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM156A | Protein FAM156A/FAM156B (Transmembrane protein 29/29B) | 4 | UniProt NCBI |
| SGSM2 | Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1) | 5 | UniProt NCBI |
| CETN3 | Centrin-3 | 5 | UniProt NCBI |
| SERGEF | Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein) | 5 | UniProt NCBI |
| CETN2 | Centrin-2 (Caltractin isoform 1) | 5 | UniProt NCBI |
| TWIST1 | Twist-related protein 1 (Class A basic helix-loop-helix protein 38) (bHLHa38) (H-twist) | 5 | UniProt NCBI |
| SGSM1 | Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2) | 5 | UniProt NCBI |
| CCDC191 | Coiled-coil domain-containing protein 191 | 2 | UniProt NCBI |
| CETN1 | Centrin-1 (Caltractin isoform 2) | 5 | UniProt NCBI |
| FBXO16 | F-box only protein 16 | 4 | UniProt NCBI |
| EFCAB11 | EF-hand calcium-binding domain-containing protein 11 | 3 | UniProt NCBI |
| SFI1 | Protein SFI1 homolog (hSFI1) | 5 | UniProt NCBI |
| POC5 | Centrosomal protein POC5 (Protein of centriole 5) (hPOC5) | 5 | UniProt NCBI |
| TDP1 | Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| CETN2 | CETN1 | 1.0 | ||
| CETN1 | EFCAB11 | 0.999 | ||
| CETN3 | CETN1 | 0.999 | ||
| CETN1 | POC5 | 0.999 |
structurally_consistent (dimer)
|
|
| CCDC191 | CETN1 | 0.999 |
structurally_consistent (dimer)
|
|
| SGSM2 | CETN1 | 0.999 | ||
| SGSM1 | CETN1 | 0.999 | ||
| CETN1 | SFI1 | 0.999 | ||
| CETN3 | CETN2 | 0.998 | 0.054 |
mutually_exclusive (Q8NA72)
|
| TDP1 | CETN1 | 0.998 | ||
| CETN2 | SGSM1 | 0.996 | ||
| FAM156A | CETN1 | 0.996 | ||
| CETN1 | FBXO16 | 0.993 | ||
| TWIST1 | CETN1 | 0.99 | ||
| CETN3 | POC5 | 0.988 | 0.134 |
structurally_consistent (dimer)
|
| CETN3 | SGSM1 | 0.984 | ||
| CETN3 | FBXO16 | 0.982 | ||
| CETN2 | EFCAB11 | 0.98 | ||
| CETN2 | POC5 | 0.98 | 0.104 |
structurally_consistent (dimer)
|
| EFCAB11 | SFI1 | 0.978 | ||
| CETN3 | EFCAB11 | 0.973 |
structurally_consistent (dimer)
|
|
| CETN3 | SFI1 | 0.971 | ||
| CETN2 | FBXO16 | 0.917 | ||
| SGSM2 | CCDC191 | 0.916 | ||
| CETN2 | SFI1 | 0.915 | ||
| CCDC191 | EFCAB11 | 0.912 | ||
| SGSM1 | CCDC191 | 0.912 | ||
| SGSM1 | EFCAB11 | 0.912 | ||
| EFCAB11 | SERGEF | 0.904 | ||
| SGSM2 | EFCAB11 | 0.902 | ||
| TDP1 | CCDC191 | 0.902 | ||
| CCDC191 | POC5 | 0.902 |
mutually_exclusive (Q12798)
|
|
| SGSM2 | SGSM1 | 0.902 | ||
| CCDC191 | SFI1 | 0.897 | ||
| SGSM1 | POC5 | 0.877 | ||
| EFCAB11 | POC5 | 0.877 |
mutually_exclusive (O15182)
|
|
| SGSM2 | POC5 | 0.868 | ||
| SFI1 | POC5 | 0.824 | ||
| TDP1 | CETN2 | 0.804 | 0.05 | |
| SGSM1 | SFI1 | 0.796 | ||
| TDP1 | SGSM1 | 0.793 | ||
| SGSM2 | SFI1 | 0.793 | ||
| TDP1 | EFCAB11 | 0.793 | ||
| SGSM2 | CETN2 | 0.702 | ||
| CETN3 | CCDC191 | 0.63 | ||
| TDP1 | SGSM2 | 0.625 | ||
| TDP1 | POC5 | 0.611 | 0.09 | |
| TDP1 | SFI1 | 0.59 | ||
| CETN2 | CCDC191 | 0.572 | ||
| TWIST1 | FAM156A | 0.572 | ||
| TWIST1 | CCDC191 | 0.572 | ||
| SGSM2 | FAM156A | 0.572 | ||
| FAM156A | EFCAB11 | 0.557 | ||
| CCDC191 | FAM156A | 0.557 | ||
| CCDC191 | FBXO16 | 0.557 | ||
| FAM156A | FBXO16 | 0.557 | ||
| SGSM1 | FAM156A | 0.557 | ||
| TWIST1 | SGSM1 | 0.502 | ||
| FAM156A | POC5 | 0.502 | ||
| TWIST1 | EFCAB11 | 0.502 | ||
| TDP1 | FAM156A | 0.502 | ||
| TWIST1 | SGSM2 | 0.502 | ||
| FAM156A | SFI1 | 0.487 | ||
| FBXO16 | EFCAB11 | 0.487 | ||
| SGSM1 | FBXO16 | 0.487 | ||
| SGSM2 | CETN3 | 0.415 | ||
| TWIST1 | CETN2 | 0.337 | ||
| TDP1 | CETN3 | 0.335 | 0.102 | |
| TWIST1 | FBXO16 | 0.333 | ||
| SGSM2 | FBXO16 | 0.333 | ||
| TWIST1 | SFI1 | 0.333 | ||
| TWIST1 | POC5 | 0.333 | ||
| CETN1 | SERGEF | 0.333 | ||
| SGSM1 | SERGEF | 0.279 | ||
| CETN3 | FAM156A | 0.18 | ||
| TDP1 | FBXO16 | 0.172 | ||
| FBXO16 | POC5 | 0.172 | ||
| TWIST1 | TDP1 | 0.172 | ||
| FBXO16 | SFI1 | 0.164 | ||
| CETN2 | FAM156A | 0.143 | ||
| CCDC191 | SERGEF | 0.13 | ||
| SGSM2 | SERGEF | 0.116 | ||
| POC5 | SERGEF | 0.086 | 0.124 | |
| TWIST1 | CETN3 | 0.084 | ||
| SFI1 | SERGEF | 0.068 | ||
| TDP1 | SERGEF | 0.064 | 0.06 | |
| CETN2 | SERGEF | 0.032 | 0.052 | |
| FAM156A | SERGEF | 0.03 | ||
| TWIST1 | SERGEF | 0.028 | ||
| FBXO16 | SERGEF | 0.027 | ||
| CETN3 | SERGEF | 0.007 | 0.078 |
Related Complexes