hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12142.1
Complex Portal: CPX-18932
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GRB10 | Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) | 5 | UniProt NCBI |
| UEVLD | Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein) | 5 | UniProt NCBI |
| WDR59 | GATOR2 complex protein WDR59 (WD repeat-containing protein 59) | 5 | UniProt NCBI |
| NRF1 | Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal) | 5 | UniProt NCBI |
| ANO1 | Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04150 | 0.0484667159694 | 0.4 | WDR59 GRB10 | mTOR signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| WDR59 | NRF1 | 0.996 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| WDR59 | UEVLD | 0.996 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GRB10 | WDR59 | 0.993 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ANO1 | WDR59 | 0.946 | 0.078 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NRF1 | UEVLD | 0.902 | 0.11 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANO1 | NRF1 | 0.902 | 0.058 | bioplex3_WMM WMM_only | |
| GRB10 | NRF1 | 0.89 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANO1 | GRB10 | 0.869 | 0.098 | bioplex3_WMM WMM_only | |
| GRB10 | UEVLD | 0.868 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANO1 | UEVLD | 0.714 | 0.15 | bioplex3_WMM WMM_only |
Related Complexes