hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
BEST1	Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)	5	UniProt NCBI
ENO1	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)	5	UniProt NCBI
ENO3	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)	5	UniProt NCBI
ENO2	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP534	0.000973512535349	0.666666666667	ENO1 ENO2	Glycolysis and gluconeogenesis
KEGG:00010	0.00143958269844	0.666666666667	ENO1 ENO2	Glycolysis / Gluconeogenesis
KEGG:01230	0.00168280767129	0.666666666667	ENO1 ENO2	Biosynthesis of amino acids
KEGG:03018	0.0019996401701	0.666666666667	ENO1 ENO2	RNA degradation
REAC:R-HSA-70263	0.00239054881557	0.666666666667	ENO1 ENO2	Gluconeogenesis
WP:WP4018	0.0031328951477	0.666666666667	ENO1 ENO2	Clear cell renal cell carcinoma pathways
KEGG:04066	0.00368672413844	0.666666666667	ENO1 ENO2	HIF-1 signaling pathway
KEGG:01200	0.00406958776216	0.666666666667	ENO1 ENO2	Carbon metabolism
WP:WP5355	0.00412431213363	0.666666666667	ENO1 ENO2	Metabolic Epileptic Disorders
GO:0004634	0.00421361424067	0.666666666667	ENO1 ENO2	phosphopyruvate hydratase activity
GO:0000015	0.00421361424067	0.666666666667	ENO1 ENO2	phosphopyruvate hydratase complex
REAC:R-HSA-70171	0.0141416283812	0.666666666667	ENO1 ENO2	Glycolysis
REAC:R-HSA-70326	0.0209338694285	0.666666666667	ENO1 ENO2	Glucose metabolism
HPA:0411283	0.0424050554332	0.333333333333	BEST1	retina; pigment epithelial cells[High]

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ENO3	ENO2	1.0	0.59	mutually_exclusive (P06733) structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
ENO1	ENO2	0.999	0.584	mutually_exclusive (P13929) structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM
ENO1	ENO3	0.999	0.822	mutually_exclusive (P09104) structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM treiber_WMM
BEST1	ENO3	0.898			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
BEST1	ENO1	0.004			bioplex3_HEK293 bioplex ()