hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12160.1
Complex Portal: CPX-18495
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNT2 | Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1) | 5 | UniProt NCBI |
| SLC43A1 | Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1) | 5 | UniProt NCBI |
| PIGQ | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) | 5 | UniProt NCBI |
| DCST1 | E3 ubiquitin-protein ligase DCST1 (EC 2.3.2.27) (DC-STAMP domain-containing protein 1) (RING-type E3 ubiquitin transferase) | 5 | UniProt NCBI |
| MARCHF4 | E3 ubiquitin-protein ligase MARCHF4 (EC 2.3.2.27) (Membrane-associated RING finger protein 4) (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174) (RING-type E3 ubiquitin transferase MARCHF4) | 5 | UniProt NCBI |
| ANO10 | Anoctamin-10 (Transmembrane protein 16K) | 5 | UniProt NCBI |
| IL10RB | Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b) | 5 | UniProt NCBI |
| OR10H2 | Olfactory receptor 10H2 (Olfactory receptor OR19-23) | 3 | UniProt NCBI |
| ANO5 | Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9733458 | 0.00286935042585 | 0.222222222222 | ANO5 ANO10 | Induction of Cell-Cell Fusion |
| CORUM:6758 | 0.0499842271994 | 0.111111111111 | IL10RB | IL10 receptor |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| OR10H2 | ANO10 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| IL10RB | OR10H2 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| OR10H2 | SLC43A1 | 0.974 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MARCHF4 | ANO5 | 0.969 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ANO5 | OR10H2 | 0.962 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MARCHF4 | KCNT2 | 0.946 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MARCHF4 | PIGQ | 0.89 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| OR10H2 | PIGQ | 0.89 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PIGQ | DCST1 | 0.878 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNT2 | DCST1 | 0.807 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNT2 | OR10H2 | 0.742 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNT2 | ANO10 | 0.607 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNT2 | PIGQ | 0.284 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ANO10 | SLC43A1 | 0.265 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| IL10RB | ANO10 | 0.25 | 0.112 | bioplex3_WMM WMM_only | |
| KCNT2 | SLC43A1 | 0.165 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ANO5 | PIGQ | 0.135 | bioplex3_WMM WMM_only | ||
| ANO5 | ANO10 | 0.113 | bioplex3_WMM WMM_only | ||
| KCNT2 | IL10RB | 0.097 | bioplex3_WMM WMM_only | ||
| ANO5 | IL10RB | 0.095 | bioplex3_WMM WMM_only | ||
| IL10RB | SLC43A1 | 0.095 | 0.146 | bioplex3_WMM WMM_only | |
| IL10RB | PIGQ | 0.087 | 0.124 | bioplex3_WMM WMM_only | |
| PIGQ | SLC43A1 | 0.085 | 0.086 | bioplex3_WMM WMM_only | |
| ANO5 | KCNT2 | 0.079 | bioplex3_WMM WMM_only | ||
| ANO10 | PIGQ | 0.079 | 0.058 | bioplex3_WMM WMM_only | |
| ANO5 | SLC43A1 | 0.078 | bioplex3_WMM WMM_only |
Related Complexes