hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12163.1
Complex Portal: CPX-12043
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDIA5 | Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) | 5 | UniProt NCBI |
| CNPY2 | Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4) | 5 | UniProt NCBI |
| MYDGF | Myeloid-derived growth factor (MYDGF) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-381038 | 0.00614555007695 | 0.666666666667 | MYDGF PDIA5 | XBP1(S) activates chaperone genes |
| REAC:R-HSA-381070 | 0.00673703034894 | 0.666666666667 | MYDGF PDIA5 | IRE1alpha activates chaperones |
| REAC:R-HSA-381119 | 0.023680221974 | 0.666666666667 | MYDGF PDIA5 | Unfolded Protein Response (UPR) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PDIA5 | CNPY2 | 0.99 | 0.028 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| PDIA5 | MYDGF | 0.958 | 0.09 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| CNPY2 | MYDGF | 0.41 | 0.366 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PDIA5 | huMAP3_00692.1 huMAP3_12163.1 huMAP3_12300.1 huMAP3_13868.1 |
| CNPY2 | huMAP3_00692.1 huMAP3_02974.1 huMAP3_12163.1 huMAP3_13047.1 |
| MYDGF | huMAP3_00692.1 huMAP3_04610.1 huMAP3_07348.1 huMAP3_12163.1 huMAP3_12300.1 huMAP3_13868.1 |