hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12170.1

Complex Portal: CPX-25265

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
TMEM220	Transmembrane protein 220	2	UniProt NCBI
MT-CYB	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	5	UniProt NCBI
COX7A2L	Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1)	4	UniProt NCBI
CASD1	N-acetylneuraminate 9-O-acetyltransferase (EC 2.3.1.45) (CAS1 domain-containing protein 1) (Sialate O-acetyltransferase) (SOAT)	5	UniProt NCBI
COX5B	Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb)	5	UniProt NCBI
COX6C	Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)	5	UniProt NCBI
UQCRFS1	Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]	5	UniProt NCBI
MT-CO3	Cytochrome c oxidase subunit 3 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide III)	5	UniProt NCBI
COX7A2	Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)	5	UniProt NCBI
LAT	Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)	5	UniProt NCBI
UQCRQ	Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)	5	UniProt NCBI
COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)	5	UniProt NCBI
PTGES2	Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) [Cleaved into: Prostaglandin E synthase 2 truncated form]	5	UniProt NCBI
GPR34	Probable G-protein coupled receptor 34	4	UniProt NCBI
UQCRC1	Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1)	5	UniProt NCBI
OPLAH	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)	5	UniProt NCBI
COX5A	Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)	5	UniProt NCBI
CPQ	Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase)	5	UniProt NCBI
LYRM7	Complex III assembly factor LYRM7 (LYR motif-containing protein 7)	5	UniProt NCBI
UNG	Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)	5	UniProt NCBI
UQCRB	Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein)	5	UniProt NCBI
ATP1B2	Sodium/potassium-transporting ATPase subunit beta-2 (Adhesion molecule in glia) (AMOG) (Sodium/potassium-dependent ATPase subunit beta-2)	5	UniProt NCBI
MT-CO1	Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)	5	UniProt NCBI
COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)	5	UniProt NCBI
COX6B1	Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04260	1.71863331867e-13	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Cardiac muscle contraction
WP:WP111	4.18886398132e-12	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Electron transport chain OXPHOS system in mitochondria
REAC:R-HSA-611105	1.19599055842e-11	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Respiratory electron transport
KEGG:00190	1.34919656935e-11	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Oxidative phosphorylation
GO:0070069	3.12640843868e-11	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	cytochrome complex
KEGG:04932	3.911794107e-11	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Non-alcoholic fatty liver disease
REAC:R-HSA-163200	6.21819770163e-11	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
WP:WP4396	6.52685554123e-11	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Nonalcoholic fatty liver disease
WP:WP4921	2.6140851905e-10	0.3125	UQCRQ UQCRC1 LYRM7 MT-CYB UQCRFS1	Mitochondrial complex III assembly
KEGG:05415	3.47541825316e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Diabetic cardiomyopathy
GO:0005746	5.78840259647e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	mitochondrial respirasome
GO:0070469	5.78840259647e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	respirasome
KEGG:05208	8.04946740305e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Chemical carcinogenesis - reactive oxygen species
KEGG:04714	9.0625190888e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Thermogenesis
REAC:R-HSA-1428517	9.41553351519e-10	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	The citric acid (TCA) cycle and respiratory electron transport
GO:0045333	1.59234216676e-09	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	cellular respiration
KEGG:05012	3.00046052975e-09	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Parkinson disease
KEGG:05020	3.78348471989e-09	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Prion disease
KEGG:05016	8.46444713909e-09	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Huntington disease
GO:0006119	8.65774660315e-09	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	oxidative phosphorylation
GO:0015980	1.98910132426e-08	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	energy derivation by oxidation of organic compounds
GO:0045275	3.10137235014e-08	0.3125	UQCRQ UQCRC1 MT-CO1 MT-CYB UQCRFS1	respiratory chain complex III
GO:0005750	3.10137235014e-08	0.3125	UQCRQ UQCRC1 MT-CO1 MT-CYB UQCRFS1	mitochondrial respiratory chain complex III
KEGG:05014	3.50171298889e-08	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Amyotrophic lateral sclerosis
GO:0019646	4.26932392178e-08	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	aerobic electron transport chain
KEGG:05010	5.12979131124e-08	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Alzheimer disease
GO:0098803	5.65167921448e-08	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	respiratory chain complex
GO:0009060	5.80133989182e-08	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	aerobic respiration
GO:0042775	7.400230899e-08	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	mitochondrial ATP synthesis coupled electron transport
GO:0042773	7.400230899e-08	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	ATP synthesis coupled electron transport
GO:0022904	1.56785971694e-07	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	respiratory electron transport chain
KEGG:05022	2.42535672623e-07	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Pathways of neurodegeneration - multiple diseases
GO:0022900	2.87124694582e-07	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	electron transport chain
GO:0006091	8.00844481221e-07	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	generation of precursor metabolites and energy
GO:0098800	4.78373317394e-06	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	inner mitochondrial membrane protein complex
KEGG:01100	8.45493803613e-06	0.625	OPLAH MT-CO1 UQCRFS1 PTGES2 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Metabolic pathways
CORUM:6442	1.07009641283e-05	0.1875	COX6C MT-CO3 MT-CO1	Cytochrome c oxidase, mitochondrial
GO:0006122	1.57308188421e-05	0.25	UQCRQ UQCRC1 MT-CYB UQCRFS1	mitochondrial electron transport, ubiquinol to cytochrome c
GO:0031966	6.41191525438e-05	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	mitochondrial membrane
GO:0005740	0.000113792283494	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	mitochondrial envelope
REAC:R-HSA-9707564	0.000122930414785	0.25	COX7A2L MT-CO1 MT-CO3 COX6C	Cytoprotection by HMOX1
GO:0005743	0.000135735013339	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	mitochondrial inner membrane
GO:0005751	0.000145197830875	0.25	COX6C MT-CO1 UQCRFS1 MT-CO3	mitochondrial respiratory chain complex IV
GO:0045277	0.000145197830875	0.25	COX6C MT-CO1 UQCRFS1 MT-CO3	respiratory chain complex IV
GO:0015453	0.000174317671505	0.3125	COX7A2L MT-CO1 MT-CYB UQCRC1 MT-CO3	oxidoreduction-driven active transmembrane transporter activity
GO:0019866	0.000212352494129	0.5	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	organelle inner membrane
HP:0000576	0.00025589262046	0.1875	MT-CO1 MT-CYB MT-CO3	Centrocecal scotoma
HP:0003200	0.000273083490545	0.25	UQCRQ MT-CO1 MT-CYB MT-CO3	Ragged-red muscle fibers
REAC:R-HSA-5628897	0.000400518675565	0.25	COX7A2L MT-CO1 MT-CO3 COX6C	TP53 Regulates Metabolic Genes
GO:0098798	0.000490362377323	0.4375	MT-CO1 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB MT-CO3	mitochondrial protein-containing complex
HP:0001427	0.000528173657558	0.1875	MT-CO1 MT-CYB MT-CO3	Mitochondrial inheritance
WP:WP4922	0.000583216073111	0.1875	COX6C MT-CO3 MT-CO1	Mitochondrial complex IV assembly
REAC:R-HSA-1430728	0.00078436318736	0.625	OPLAH MT-CO1 UQCRFS1 PTGES2 COX6C MT-CO3 UQCRC1 COX7A2L MT-CYB UQCRQ	Metabolism
HP:0200125	0.000788305236816	0.1875	MT-CO1 MT-CYB MT-CO3	Mitochondrial respiratory chain defects
HP:0003287	0.000991880180733	0.3125	UQCRQ MT-CO1 LYRM7 MT-CYB MT-CO3	Abnormality of mitochondrial metabolism
HP:0003128	0.00104923233174	0.3125	LYRM7 MT-CO1 MT-CO3 MT-CYB UQCRFS1	Lactic acidosis
HP:0002401	0.0011218361298	0.1875	MT-CO1 MT-CYB MT-CO3	Stroke-like episode
HP:0001941	0.00144158946067	0.375	MT-CO1 UQCRFS1 UQCRQ LYRM7 MT-CYB MT-CO3	Acidosis
GO:0015078	0.00183123810191	0.3125	COX7A2L MT-CO1 MT-CYB UQCRC1 MT-CO3	proton transmembrane transporter activity
HP:0012103	0.00187062362807	0.3125	UQCRQ MT-CO1 LYRM7 MT-CYB MT-CO3	Abnormality of the mitochondrion
HP:0004360	0.00204189143185	0.375	MT-CO1 UQCRFS1 UQCRQ LYRM7 MT-CYB MT-CO3	Abnormality of acid-base homeostasis
HP:0001716	0.0020448641711	0.1875	MT-CO1 MT-CYB MT-CO3	Wolff-Parkinson-White syndrome
HP:0007763	0.00233542793101	0.1875	MT-CO1 MT-CYB MT-CO3	Retinal telangiectasia
GO:0009055	0.0023922688416	0.3125	COX7A2L MT-CO1 MT-CYB UQCRC1 MT-CO3	electron transfer activity
HP:0004309	0.0033683094759	0.1875	MT-CO1 MT-CYB MT-CO3	Ventricular preexcitation
HP:0012707	0.00420218093937	0.1875	MT-CO1 MT-CO3 LYRM7	Elevated brain lactate level by MRS
HP:0025045	0.00466597362099	0.1875	MT-CO1 MT-CO3 LYRM7	Abnormal brain lactate level by MRS
GO:1990204	0.00493300424918	0.3125	UQCRQ UQCRC1 MT-CO1 MT-CYB UQCRFS1	oxidoreductase complex
HP:0007924	0.00516245143257	0.1875	MT-CO1 MT-CYB MT-CO3	Slow decrease in visual acuity
GO:0031975	0.00582261365072	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	envelope
GO:0031967	0.00582261365072	0.5625	MT-CO1 UQCRFS1 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	organelle envelope
GO:0005739	0.00633357894274	0.625	MT-CO1 UQCRFS1 PTGES2 COX6C MT-CO3 UQCRC1 COX7A2L LYRM7 MT-CYB UQCRQ	mitochondrion
HPA:0360053	0.00807591239124	0.5	MT-CO1 PTGES2 UQCRFS1 COX6C UQCRQ UQCRC1 MT-CYB LYRM7	parathyroid gland; glandular cells[High]
HP:0000622	0.00888806997289	0.1875	MT-CO1 MT-CYB MT-CO3	Blurred vision
GO:0015399	0.00963079204683	0.3125	COX7A2L MT-CO1 MT-CYB UQCRC1 MT-CO3	primary active transmembrane transporter activity
HPA:0241103	0.0103225061783	0.4375	MT-CO1 PTGES2 UQCRFS1 COX6C LYRM7 UQCRC1 UQCRQ	heart muscle; cardiomyocytes[High]
HP:0000408	0.0104401119386	0.1875	MT-CO1 MT-CYB MT-CO3	Progressive sensorineural hearing impairment
REAC:R-HSA-9711123	0.0112531558657	0.25	COX7A2L MT-CO1 MT-CO3 COX6C	Cellular response to chemical stress
HP:0000603	0.0112790736889	0.1875	MT-CO1 MT-CYB MT-CO3	Central scotoma
HP:0012377	0.0140603735653	0.1875	MT-CO1 MT-CYB MT-CO3	Hemianopia
HP:0011017	0.0147269637575	0.375	MT-CO1 LAT UQCRQ MT-CO3 MT-CYB LYRM7	Abnormal cellular physiology
GO:0004129	0.0152921671063	0.1875	COX7A2L MT-CO3 MT-CO1	cytochrome-c oxidase activity
GO:0016675	0.0152921671063	0.1875	COX7A2L MT-CO3 MT-CO1	oxidoreductase activity, acting on a heme group of donors
WP:WP5380	0.0160973970252	0.1875	COX6C MT-CO3 MT-CO1	5q35 copy number variation
HP:0001730	0.0172602972632	0.1875	MT-CO1 MT-CYB MT-CO3	Progressive hearing impairment
HP:0002572	0.0184248280836	0.1875	MT-CO1 MT-CYB MT-CO3	Episodic vomiting
HP:0025354	0.0191138364928	0.375	MT-CO1 LAT UQCRQ MT-CO3 MT-CYB LYRM7	Abnormal cellular phenotype
HPA:0271111	0.0207484949628	0.25	COX6C MT-CO1 UQCRFS1 UQCRC1	kidney; bowman's capsule[>=Low]
HPA:0271132	0.0217275879178	0.3125	COX6C CPQ MT-CO1 UQCRFS1 UQCRC1	kidney; distal tubules[>=Medium]
GO:0022853	0.0219521092167	0.3125	COX7A2L MT-CO1 MT-CYB UQCRC1 MT-CO3	active monoatomic ion transmembrane transporter activity
HPA:0271142	0.023447545392	0.3125	COX6C CPQ MT-CO1 UQCRFS1 UQCRC1	kidney; proximal tubules (cell body)[>=Medium]
HP:0012841	0.0250281461283	0.1875	MT-CO1 MT-CYB MT-CO3	Retinal vascular tortuosity
HP:0012544	0.0255674550878	0.125	MT-CO1 MT-CO3	Elevated circulating aldolase concentration
HP:0003652	0.0255674550878	0.125	MT-CO1 MT-CO3	Recurrent myoglobinuria
HP:0012705	0.0265121239957	0.1875	MT-CO1 MT-CO3 LYRM7	Abnormal metabolic brain imaging by MRS
HP:0002174	0.0265121239957	0.1875	MT-CO1 MT-CYB MT-CO3	Postural tremor
HP:0003737	0.0280529203225	0.1875	MT-CO1 MT-CYB MT-CO3	Mitochondrial myopathy
GO:0006123	0.0298827994283	0.1875	COX6C MT-CO3 MT-CO1	mitochondrial electron transport, cytochrome c to oxygen
HP:0001271	0.0313090231411	0.1875	UQCRC1 MT-CYB MT-CO3	Polyneuropathy
HPA:0310433	0.0319345852066	0.375	LAT MT-CO1 UQCRFS1 COX6C LYRM7 UQCRC1	lymph node; germinal center cells[High]
HP:0030234	0.0340681699649	0.125	MT-CO1 MT-CO3	Highly elevated creatine kinase
HPA:0271133	0.0353490287693	0.25	COX6C MT-CO1 UQCRFS1 UQCRC1	kidney; distal tubules[High]
HP:0000544	0.0366445831328	0.1875	MT-CO1 MT-CO3 LYRM7	External ophthalmoplegia
HP:0001112	0.043773961294	0.125	MT-CYB MT-CO3	Leber optic atrophy
HP:0008619	0.0490397781719	0.1875	MT-CO1 MT-CYB MT-CO3	Bilateral sensorineural hearing impairment
CORUM:2909	0.0497620750785	0.0625	LAT	PLC-gamma-2-Syk-LAT-FcR-gamma complex
CORUM:2913	0.0497620750785	0.0625	LAT	PLC-gamma-2-LAT complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
COX5A	COX4I1	0.999	0.984	structurally_consistent (dimer)
UQCRB	UQCRC1	0.999	0.986
LYRM7	UQCRFS1	0.998	0.07
UQCRQ	PTGES2	0.998	0.11
UQCRQ	UQCRC1	0.998	0.962
UQCRFS1	UQCRC1	0.997	0.988	structurally_consistent (dimer)
UQCRB	UQCRQ	0.996	0.992	structurally_consistent (P22695) structurally_consistent (dimer)
COX7A2L	UQCRQ	0.995	0.726
MT-CYB	UQCRQ	0.995	0.77	structurally_consistent (dimer)
UQCRC1	COX4I1	0.995	0.904
UQCRC1	COX5B	0.995	0.748
UQCRFS1	COX5B	0.994	0.686	mutually_exclusive (P22695)
UQCRB	COX6C	0.994	0.944
COX7A2L	COX5A	0.993	0.686
UQCRB	PTGES2	0.993	0.122	structurally_consistent (P00156) structurally_consistent (dimer)
MT-CO3	COX4I1	0.992	0.774	structurally_consistent (P00395) structurally_consistent (dimer)
UQCRQ	COX6C	0.992	0.936	mutually_exclusive (P00403)
UQCRFS1	PTGES2	0.992	0.126
UQCRFS1	UQCRQ	0.992	0.986	structurally_consistent (dimer)
UNG	UQCRFS1	0.991	0.084
PTGES2	UQCRC1	0.99	0.228
COX6C	COX6A1	0.99	0.602
COX7A2L	UQCRB	0.989	0.882
COX7A2	COX6B1	0.988	0.952	structurally_consistent (P00414)
COX6B1	COX6A1	0.986	0.766
UQCRFS1	UQCRB	0.985	0.98
MT-CYB	PTGES2	0.985	0.276	structurally_consistent (dimer)
UQCRFS1	COX4I1	0.985	0.908	mutually_exclusive (P22695) structurally_consistent (dimer)
COX6B1	COX4I1	0.984	0.83	structurally_consistent (P00403) structurally_consistent (dimer)
COX7A2	COX4I1	0.984	0.716	structurally_consistent (P00403)
COX7A2L	MT-CYB	0.983	0.652
MT-CYB	UQCRB	0.981	0.814	structurally_consistent (Q9H7Z7) structurally_consistent (dimer)
MT-CO3	COX6A1	0.98	0.454
COX7A2L	UQCRC1	0.979	0.584
COX6C	COX4I1	0.975	0.96	structurally_consistent (dimer)
COX7A2L	PTGES2	0.973	0.06
MT-CO1	UQCRQ	0.972	0.492	mutually_exclusive (P00403)
COX7A2L	COX6A1	0.972	0.784
MT-CO1	COX4I1	0.968	0.776	structurally_consistent (dimer)
MT-CO3	MT-CO1	0.967	0.52	structurally_consistent (dimer)
COX5A	COX6C	0.967	0.904
COX7A2L	MT-CO1	0.967	0.424
MT-CO1	COX6C	0.967	0.908
COX6A1	COX4I1	0.966	0.672	structurally_consistent (P00395)
COX7A2L	COX6C	0.965	0.834
COX7A2L	COX5B	0.964	0.788
MT-CO1	COX6A1	0.963	0.632	structurally_consistent (dimer)
COX6A1	COX5B	0.962	0.654
MT-CO1	UQCRB	0.961	0.898
COX7A2	UQCRFS1	0.958	0.89
UQCRQ	COX6B1	0.958	0.58	structurally_consistent (P47985)
COX7A2L	COX6B1	0.957	0.696
COX7A2L	COX4I1	0.957	0.814
UQCRC1	COX6A1	0.955	0.466	structurally_consistent (P47985)
COX6B1	UQCRC1	0.953	0.782	structurally_consistent (P47985)
UQCRB	COX6A1	0.953	0.836
COX7A2L	MT-CO3	0.952	0.198
UQCRQ	COX6A1	0.952	0.756
UQCRFS1	MT-CYB	0.951	0.842	structurally_consistent (dimer)
COX6B1	COX5B	0.951	0.916	structurally_consistent (P00414)
MT-CO1	COX5A	0.95	0.616
COX7A2	COX6A1	0.949	0.652
COX5A	UQCRC1	0.947	0.888
MT-CYB	UQCRC1	0.944	0.762
UQCRB	COX4I1	0.943	0.936	structurally_consistent (P22695)
OPLAH	PTGES2	0.94	0.11
MT-CO3	COX6C	0.939	0.824	structurally_consistent (P13073)
ATP1B2	UQCRB	0.938
COX4I1	COX5B	0.936	0.894
UQCRQ	COX4I1	0.931	0.82
COX5A	UQCRQ	0.93	0.792
MT-CO1	UQCRC1	0.928	0.836
COX7A2	COX5B	0.927	0.768
COX6B1	TMEM220	0.927
COX6C	UQCRC1	0.927	0.95
COX5A	COX6A1	0.927	0.62
PTGES2	COX4I1	0.921	0.154	mutually_exclusive (P22695)
COX5A	UQCRFS1	0.919	0.884	mutually_exclusive (P13073)
COX6B1	COX6C	0.917	0.91	structurally_consistent (P00403)
LYRM7	UQCRQ	0.917	0.018
COX5A	COX5B	0.917	0.704	structurally_consistent (P00414)
MT-CO3	COX7A2	0.915	0.688	structurally_consistent (dimer)
MT-CO3	UQCRC1	0.903	0.618
MT-CO3	UQCRQ	0.902	0.694
COX7A2L	UQCRFS1	0.899	0.82
GPR34	COX4I1	0.886
UQCRB	COX5B	0.886	0.92
COX7A2	COX6C	0.88	0.848
COX5A	UQCRB	0.875	0.856
UQCRB	COX6B1	0.874	0.864
MT-CO1	COX6B1	0.873	0.786	structurally_consistent (P13073)
MT-CO3	COX6B1	0.871	0.52	structurally_consistent (P13073) structurally_consistent (dimer)
MT-CO1	COX5B	0.868	0.898
LAT	COX5B	0.865
COX5A	COX7A2	0.862	0.906	structurally_consistent (P00414)
COX6C	COX5B	0.853	0.922
UQCRC1	TMEM220	0.853
UQCRFS1	COX6B1	0.842	0.71	structurally_consistent (P13073) structurally_consistent (dimer)
COX7A2L	COX7A2	0.838	0.686
CPQ	COX7A2L	0.828	0.05
MT-CO3	COX5A	0.824	0.732	structurally_consistent (dimer)
MT-CO1	MT-CYB	0.824	0.734
MT-CO3	UQCRB	0.823	0.666
COX6B1	CASD1	0.822		structurally_consistent (dimer)
LYRM7	COX4I1	0.807	0.114
LYRM7	UNG	0.78	0.016
LYRM7	UQCRC1	0.754	0.25
UQCRFS1	COX6A1	0.748	0.674	structurally_consistent (dimer)
MT-CYB	OPLAH	0.73	0.036
MT-CO3	COX5B	0.706	0.428	structurally_consistent (dimer)
COX7A2L	GPR34	0.678
COX7A2	UQCRC1	0.676	0.802
MT-CYB	COX6B1	0.676	0.448	mutually_exclusive (P47985)
CPQ	COX7A2	0.648	0.0769380530973
LYRM7	UQCRB	0.639	0.02
MT-CO1	COX7A2	0.622	0.814
COX7A2	GPR34	0.591
LYRM7	COX5A	0.578	0.11
COX7A2	UQCRQ	0.562	0.85
GPR34	UQCRC1	0.498
GPR34	COX5B	0.497
PTGES2	COX5B	0.463	0.086	mutually_exclusive (P22695)
MT-CYB	COX4I1	0.444	0.648
COX7A2	UNG	0.413	0.056
COX7A2L	OPLAH	0.41	0.042
COX5A	UNG	0.394	0.206
COX5A	COX6B1	0.389	0.856	structurally_consistent (P13073)
COX7A2	UQCRB	0.386	0.972
UNG	UQCRC1	0.379	0.138
UQCRQ	COX5B	0.375	0.656
LYRM7	COX7A2	0.374	0.07
UQCRFS1	OPLAH	0.358	0.0982962962963
COX7A2	OPLAH	0.356	0.04
MT-CO1	PTGES2	0.291	0.156
UQCRB	CASD1	0.255
CPQ	UQCRQ	0.254	0.05
MT-CO1	UQCRFS1	0.246	0.69	mutually_exclusive (P13073)
UNG	COX4I1	0.244	0.176
COX6C	CASD1	0.236
UQCRQ	OPLAH	0.229	0.066
UNG	PTGES2	0.227	0.06
COX6C	PTGES2	0.225	0.07
OPLAH	UQCRC1	0.224	0.062
COX5A	PTGES2	0.219	0.184
UQCRC1	CASD1	0.219
COX5A	TMEM220	0.215
MT-CYB	COX5B	0.203	0.482
UNG	COX5B	0.198	0.054
LYRM7	COX5B	0.17	0.104
LYRM7	PTGES2	0.163	0.036
UQCRB	TMEM220	0.158
MT-CYB	COX6C	0.157	0.624
UNG	UQCRB	0.153	0.056
COX5B	CASD1	0.147
LYRM7	COX7A2L	0.145	0.022
MT-CO3	MT-CYB	0.133	0.578
COX6B1	PTGES2	0.133	0.084
COX7A2	PTGES2	0.12	0.0883339882122
UQCRB	OPLAH	0.12	0.038
UNG	UQCRQ	0.115	0.038
MT-CO3	UQCRFS1	0.107	0.536
LYRM7	MT-CYB	0.103	0.086
COX5A	MT-CYB	0.097	0.448
CPQ	COX5A	0.092	0.058
LYRM7	COX6A1	0.085	0.084
COX5B	TMEM220	0.078
UNG	MT-CYB	0.076	0.066
COX7A2L	UNG	0.076	0.022
LYRM7	MT-CO1	0.076	0.02
GPR34	COX6C	0.073
COX5A	CASD1	0.073
UQCRFS1	COX6C	0.071	0.764
LYRM7	COX6B1	0.068	0.046
COX7A2	MT-CYB	0.063	0.44
COX5A	LAT	0.058
UQCRB	GPR34	0.052
LYRM7	MT-CO3	0.045	0.06
LYRM7	COX6C	0.043	0.09
CPQ	UQCRFS1	0.039	0.052
COX5A	GPR34	0.032
UQCRFS1	GPR34	0.031
MT-CO1	OPLAH	0.026	0.022
MT-CO3	PTGES2	0.022	0.086
COX4I1	CASD1	0.021
CPQ	COX4I1	0.018	0.05
LAT	COX4I1	0.016
ATP1B2	COX4I1	0.015
ATP1B2	COX6C	0.015
OPLAH	COX4I1	0.013	0.082
ATP1B2	UQCRC1	0.013
ATP1B2	COX5B	0.013
OPLAH	COX6C	0.011	0.07
OPLAH	COX5B	0.01	0.048
PTGES2	COX6A1	0.01	0.22
COX5A	ATP1B2	0.009
UQCRFS1	ATP1B2	0.008
LAT	UQCRC1	0.007
UQCRFS1	CASD1	0.006

Related Complexes

Genename	Complexes
TMEM220	huMAP3_11289.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_13252.1 huMAP3_14327.1 huMAP3_14580.1 huMAP3_14778.1 huMAP3_14824.1 huMAP3_14899.1
MT-CYB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX7A2L	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
CASD1	huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_13252.1 huMAP3_14580.1 huMAP3_14899.1
COX5B	huMAP3_09875.1 huMAP3_10725.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
COX6C	huMAP3_04820.1 huMAP3_07696.1 huMAP3_10623.1 huMAP3_10718.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
UQCRFS1	huMAP3_01826.1 huMAP3_04728.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09982.1 huMAP3_10294.1 huMAP3_10458.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14580.1
MT-CO3	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX7A2	huMAP3_01629.1 huMAP3_03863.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
LAT	huMAP3_02776.1 huMAP3_04776.1 huMAP3_09792.1 huMAP3_10414.1 huMAP3_10963.1 huMAP3_11385.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12584.1 huMAP3_12668.1 huMAP3_12850.1 huMAP3_14482.1 huMAP3_14580.1
UQCRQ	huMAP3_02983.1 huMAP3_05463.1 huMAP3_06133.1 huMAP3_07069.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX6A1	huMAP3_07005.1 huMAP3_08546.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
PTGES2	huMAP3_05353.1 huMAP3_08546.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_12970.1 huMAP3_14560.1 huMAP3_14580.1
GPR34	huMAP3_04059.1 huMAP3_08849.1 huMAP3_09567.1 huMAP3_10425.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_12632.1 huMAP3_13633.1 huMAP3_14064.1 huMAP3_14580.1
UQCRC1	huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_09982.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14560.1 huMAP3_14580.1
OPLAH	huMAP3_03184.1 huMAP3_06551.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12970.1 huMAP3_13084.1 huMAP3_14560.1 huMAP3_14580.1
COX5A	huMAP3_01464.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
CPQ	huMAP3_00058.1 huMAP3_05963.1 huMAP3_08838.1 huMAP3_11861.1 huMAP3_11952.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_13274.1 huMAP3_14560.1 huMAP3_14580.1
LYRM7	huMAP3_00475.1 huMAP3_01826.1 huMAP3_04728.1 huMAP3_06034.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09941.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
UNG	huMAP3_01826.1 huMAP3_03561.1 huMAP3_04728.1 huMAP3_05671.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_08389.1 huMAP3_09058.1 huMAP3_10294.1 huMAP3_10341.1 huMAP3_10623.1 huMAP3_10642.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12510.1 huMAP3_14580.1
UQCRB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
ATP1B2	huMAP3_02138.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12708.1 huMAP3_14315.1 huMAP3_14560.1 huMAP3_14580.1
MT-CO1	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07696.1 huMAP3_07840.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX4I1	huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_10725.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
COX6B1	huMAP3_03863.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_13252.1 huMAP3_14580.1 huMAP3_14899.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_12170.1

Complex Portal: CPX-25265