hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12197.1
Complex Portal: CPX-6154
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MPC1 | Mitochondrial pyruvate carrier 1 (Brain protein 44-like protein) | 5 | UniProt NCBI |
| MPC2 | Mitochondrial pyruvate carrier 2 (Brain protein 44) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP534 | 0.00036647347272 | 1.0 | MPC1 MPC2 | Glycolysis and gluconeogenesis |
| GO:0006850 | 0.000468200720083 | 1.0 | MPC1 MPC2 | mitochondrial pyruvate transmembrane transport |
| REAC:R-HSA-70268 | 0.000743311362176 | 1.0 | MPC1 MPC2 | Pyruvate metabolism |
| WP:WP5355 | 0.00155570330173 | 1.0 | MPC1 MPC2 | Metabolic Epileptic Disorders |
| REAC:R-HSA-71406 | 0.00226581808332 | 1.0 | MPC1 MPC2 | Pyruvate metabolism and Citric Acid (TCA) cycle |
| KEGG:05415 | 0.00267768543767 | 1.0 | MPC1 MPC2 | Diabetic cardiomyopathy |
| GO:0050833 | 0.0028092043205 | 1.0 | MPC1 MPC2 | pyruvate transmembrane transporter activity |
| GO:1901475 | 0.0028092043205 | 1.0 | MPC1 MPC2 | pyruvate transmembrane transport |
| GO:0006848 | 0.00468200720083 | 1.0 | MPC1 MPC2 | pyruvate transport |
| REAC:R-HSA-1428517 | 0.0242575818332 | 1.0 | MPC1 MPC2 | The citric acid (TCA) cycle and respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MPC2 | MPC1 | 0.941 | 0.55 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MPC1 | huMAP3_12197.1 |
| MPC2 | huMAP3_00962.1 huMAP3_01257.1 huMAP3_05951.1 huMAP3_12197.1 |