hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12212.1
Complex Portal: CPX-14283
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM129 | E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) | 5 | UniProt NCBI |
| SLC35E2B | Solute carrier family 35 member E2B | 3 | UniProt NCBI |
| KCNQ5 | Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5) | 5 | UniProt NCBI |
| KCNA2 | Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) | 5 | UniProt NCBI |
| UTS2R | Urotensin-2 receptor (UR-2-R) (G-protein coupled receptor 14) (Urotensin II receptor) (UR-II-R) | 5 | UniProt NCBI |
| KCNA3 | Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 0.00492422076745 | 0.4 | KCNQ5 KCNA3 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.0323221445549 | 0.4 | KCNQ5 KCNA3 | Potassium Channels |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNA2 | KCNA3 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KCNA2 | UTS2R | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TMEM129 | KCNA2 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNA2 | KCNQ5 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNA2 | SLC35E2B | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TMEM129 | SLC35E2B | 0.415 | bioplex3_WMM WMM_only | ||
| TMEM129 | KCNA3 | 0.415 | bioplex3_WMM WMM_only | ||
| SLC35E2B | KCNA3 | 0.415 | bioplex3_WMM WMM_only | ||
| TMEM129 | UTS2R | 0.278 | bioplex3_WMM WMM_only | ||
| KCNA3 | UTS2R | 0.25 | bioplex3_WMM WMM_only | ||
| SLC35E2B | UTS2R | 0.25 | bioplex3_WMM WMM_only | ||
| TMEM129 | KCNQ5 | 0.21 | bioplex3_WMM WMM_only | ||
| KCNQ5 | KCNA3 | 0.095 | bioplex3_WMM WMM_only | ||
| KCNQ5 | SLC35E2B | 0.095 | bioplex3_WMM WMM_only | ||
| KCNQ5 | UTS2R | 0.078 | bioplex3_WMM WMM_only |
Related Complexes