hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12238.1
Complex Portal: CPX-23685
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HMGN5 | High mobility group nucleosome-binding domain-containing protein 5 (Nucleosome-binding protein 1) | 4 | UniProt NCBI |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) | 5 | UniProt NCBI |
| ACO2 | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) | 5 | UniProt NCBI |
| ARMT1 | Damage-control phosphatase ARMT1 (EC 3.1.3.-) (Acidic residue methyltransferase 1) (Protein-glutamate O-methyltransferase) (EC 2.1.1.-) (Sugar phosphate phosphatase ARMT1) | 5 | UniProt NCBI |
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO (Fat mass and obesity-associated protein) (U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (EC 1.14.11.-) (U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO) (EC 1.14.11.-) (mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (m6A(m)-demethylase FTO) (EC 1.14.11.-) (mRNA N(6)-methyladenosine demethylase FTO) (EC 1.14.11.53) (tRNA N1-methyl adenine demethylase FTO) (EC 1.14.11.-) | 5 | UniProt NCBI |
| NLN | Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase) | 5 | UniProt NCBI |
| ARHGAP1 | Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP) | 5 | UniProt NCBI |
| ARPIN | Arpin (Arp2/3 inhibition protein) | 5 | UniProt NCBI |
| PAK2 | Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FTO | HIBCH | 0.946 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| NLN | FTO | 0.931 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| HIBCH | ARHGAP1 | 0.913 | 0.2 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAK2 | ARMT1 | 0.902 | 0.164 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM | |
| ARPIN | NLN | 0.879 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAK2 | HIBCH | 0.876 | 0.076 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ACO2 | HIBCH | 0.87 | 0.442 | bioplex_WMM bioplex3_WMM fraction | |
| PAK2 | FTO | 0.846 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| NLN | ARMT1 | 0.842 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARMT1 | HIBCH | 0.839 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARPIN | HIBCH | 0.828 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only | |
| FTO | HMGN5 | 0.824 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARPIN | FTO | 0.778 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARPIN | HMGN5 | 0.752 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAK2 | HMGN5 | 0.69 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAK2 | ARHGAP1 | 0.676 | 0.188 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| NLN | HIBCH | 0.668 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARMT1 | ARHGAP1 | 0.648 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| HMGN5 | HIBCH | 0.61 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| NLN | HMGN5 | 0.607 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARMT1 | ACO2 | 0.583 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only | |
| NLN | PAK2 | 0.579 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARMT1 | FTO | 0.536 | 0.058 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ARMT1 | HMGN5 | 0.535 | 0.01 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAK2 | ACO2 | 0.472 | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| FTO | ACO2 | 0.469 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| NLN | ACO2 | 0.469 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| NLN | ARHGAP1 | 0.331 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARPIN | PAK2 | 0.317 | 0.168 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ARPIN | ACO2 | 0.225 | 0.126 | bioplex_WMM bioplex3_WMM WMM_only | |
| FTO | ARHGAP1 | 0.148 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| ACO2 | ARHGAP1 | 0.114 | 0.264 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| ARPIN | ARHGAP1 | 0.112 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | |
| HMGN5 | ARHGAP1 | 0.071 | 0.016 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARPIN | ARMT1 | 0.07 | 0.016 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ACO2 | HMGN5 | 0.057 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| HMGN5 | huMAP3_12238.1 huMAP3_15220.1 |
| HIBCH | huMAP3_12238.1 |
| ACO2 | huMAP3_12073.1 huMAP3_12238.1 |
| ARMT1 | huMAP3_05729.1 huMAP3_08704.1 huMAP3_12238.1 huMAP3_13658.1 |
| FTO | huMAP3_07841.1 huMAP3_12238.1 |
| NLN | huMAP3_02296.1 huMAP3_05130.1 huMAP3_09103.1 huMAP3_09219.1 huMAP3_12238.1 |
| ARHGAP1 | huMAP3_12238.1 |
| ARPIN | huMAP3_01493.1 huMAP3_12238.1 huMAP3_14421.1 |
| PAK2 | huMAP3_05415.1 huMAP3_12238.1 huMAP3_12610.1 huMAP3_13927.1 |