hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12258.1
Complex Portal: CPX-19782
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FXYD1 | Phospholemman (FXYD domain-containing ion transport regulator 1) (Sodium/potassium-transporting ATPase subunit FXYD1) | 5 | UniProt NCBI |
| NDRG3 | Protein NDRG3 (N-myc downstream-regulated gene 3 protein) | 3 | UniProt NCBI |
| ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1) | 5 | UniProt NCBI |
| PANK1 | Pantothenate kinase 1 (hPanK) (hPanK1) (EC 2.7.1.33) (Pantothenic acid kinase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-936837 | 0.00718390333861 | 0.5 | ATP1B1 FXYD1 | Ion transport by P-type ATPases |
| REAC:R-HSA-5578775 | 0.00837722051003 | 0.5 | ATP1B1 FXYD1 | Ion homeostasis |
| GO:1903276 | 0.0168521501606 | 0.5 | ATP1B1 FXYD1 | regulation of sodium ion export across plasma membrane |
| GO:1903278 | 0.0168521501606 | 0.5 | ATP1B1 FXYD1 | positive regulation of sodium ion export across plasma membrane |
| KEGG:04024 | 0.0306683825257 | 0.5 | ATP1B1 FXYD1 | cAMP signaling pathway |
| REAC:R-HSA-5576891 | 0.0363250695065 | 0.5 | ATP1B1 FXYD1 | Cardiac conduction |
| REAC:R-HSA-9679191 | 0.0363250695065 | 0.5 | ATP1B1 FXYD1 | Potential therapeutics for SARS |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NDRG3 | ATP1B1 | 0.979 | 0.016 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NDRG3 | FXYD1 | 0.939 | bioplex3_HEK293 bioplex () | ||
| ATP1B1 | PANK1 | 0.85 | 0.082 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NDRG3 | PANK1 | 0.768 | 0.064 | bioplex3_WMM WMM_only | |
| ATP1B1 | FXYD1 | 0.193 | bioplex3_HEK293 bioplex () |
Related Complexes