hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12285.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PASK | PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1) | 5 | UniProt NCBI |
| WNT7B | Protein Wnt-7b | 5 | UniProt NCBI |
| PTPN18 | Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase) | 5 | UniProt NCBI |
| WNT4 | Protein Wnt-4 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4150 | 0.00142851438729 | 0.5 | WNT7B WNT4 | Wnt signaling in kidney disease |
| REAC:R-HSA-3238698 | 0.00306932002175 | 0.5 | WNT7B WNT4 | WNT ligand biogenesis and trafficking |
| KEGG:05217 | 0.00370671577133 | 0.5 | WNT7B WNT4 | Basal cell carcinoma |
| WP:WP4336 | 0.00685264055756 | 0.5 | WNT7B WNT4 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| KEGG:04916 | 0.00847251296121 | 0.5 | WNT7B WNT4 | Melanogenesis |
| WP:WP4258 | 0.00862655865142 | 0.5 | WNT7B WNT4 | lncRNA in canonical Wnt signaling and colorectal cancer |
| WP:WP399 | 0.0110692711707 | 0.5 | WNT7B WNT4 | Wnt signaling pathway and pluripotency |
| WP:WP3931 | 0.0125286636678 | 0.5 | WNT7B WNT4 | Embryonic stem cell pluripotency pathways |
| WP:WP710 | 0.0127805971611 | 0.5 | WNT7B WNT4 | DNA damage response only ATM dependent |
| WP:WP428 | 0.0127805971611 | 0.5 | WNT7B WNT4 | Wnt signaling |
| WP:WP4787 | 0.0130350149263 | 0.5 | WNT7B WNT4 | Osteoblast differentiation and related diseases |
| KEGG:04550 | 0.0177164397058 | 0.5 | WNT7B WNT4 | Signaling pathways regulating pluripotency of stem cells |
| KEGG:04934 | 0.0192212154966 | 0.5 | WNT7B WNT4 | Cushing syndrome |
| KEGG:05224 | 0.0198400959038 | 0.5 | WNT7B WNT4 | Breast cancer |
| KEGG:05226 | 0.0211069184789 | 0.5 | WNT7B WNT4 | Gastric cancer |
| WP:WP4239 | 0.0218193051527 | 0.5 | WNT7B WNT4 | Epithelial to mesenchymal transition in colorectal cancer |
| WP:WP4262 | 0.0221503925292 | 0.5 | WNT7B WNT4 | Breast cancer pathway |
| REAC:R-HSA-373080 | 0.0232149434748 | 0.5 | WNT7B WNT4 | Class B/2 (Secretin family receptors) |
| KEGG:04390 | 0.02620193588 | 0.5 | WNT7B WNT4 | Hippo signaling pathway |
| KEGG:04150 | 0.0269222811984 | 0.5 | WNT7B WNT4 | mTOR signaling pathway |
| KEGG:04310 | 0.0276522587106 | 0.5 | WNT7B WNT4 | Wnt signaling pathway |
| KEGG:05225 | 0.0310562109 | 0.5 | WNT7B WNT4 | Hepatocellular carcinoma |
| KEGG:05205 | 0.0406374666322 | 0.5 | WNT7B WNT4 | Proteoglycans in cancer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| WNT7B | WNT4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| WNT4 | PASK | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PTPN18 | PASK | 0.951 | 0.064 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| WNT7B | PASK | 0.148 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes