hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12290.1

Complex Portal: CPX-23984

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
ATP8A1	Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1)	5	UniProt NCBI
TEX2	Testis-expressed protein 2 (Transmembrane protein 96)	4	UniProt NCBI
SLC6A20	Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP5029	0.0331010360575	0.333333333333	SLC6A20	Amino acid transport defects IEMs
REAC:R-HSA-5619101	0.0498224659464	0.333333333333	SLC6A20	Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)
REAC:R-HSA-5660686	0.0498224659464	0.333333333333	SLC6A20	Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ATP8A1	SLC6A20	0.988			bioplex3_HEK293 bioplex3_WMM WMM_only
TEX2	SLC6A20	0.946			bioplex3_HEK293 bioplex3_WMM WMM_only
TEX2	ATP8A1	0.076	0.102		bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
ATP8A1	huMAP3_02927.1 huMAP3_07269.1 huMAP3_09901.1 huMAP3_10102.1 huMAP3_11603.1 huMAP3_12290.1 huMAP3_12718.1 huMAP3_15029.1
TEX2	huMAP3_01854.1 huMAP3_05065.1 huMAP3_05358.1 huMAP3_05938.1 huMAP3_07084.1 huMAP3_08559.1 huMAP3_09313.1 huMAP3_09763.1 huMAP3_12290.1 huMAP3_12718.1
SLC6A20	huMAP3_02927.1 huMAP3_04589.1 huMAP3_09901.1 huMAP3_10011.1 huMAP3_10102.1 huMAP3_12290.1 huMAP3_12718.1