hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12340.1
Complex Portal: CPX-12217
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MYCT1 | Myc target protein 1 (Myc target in myeloid cells protein 1) | 4 | UniProt NCBI |
| DDR2 | Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b) | 5 | UniProt NCBI |
| DDR1 | Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) | 5 | UniProt NCBI |
| GPR83 | G-protein coupled receptor 83 (G-protein coupled receptor 72) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0038062 | 0.0028092043205 | 0.5 | DDR2 DDR1 | protein tyrosine kinase collagen receptor activity |
| REAC:R-HSA-3000171 | 0.0115164156767 | 0.5 | DDR2 DDR1 | Non-integrin membrane-ECM interactions |
| GO:0038064 | 0.0168521501606 | 0.5 | DDR2 DDR1 | collagen receptor activity |
| GO:0038063 | 0.0280843539964 | 0.5 | DDR2 DDR1 | collagen-activated tyrosine kinase receptor signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DDR1 | MYCT1 | 0.911 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DDR1 | DDR2 | 0.899 | 0.096 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DDR1 | GPR83 | 0.841 | bioplex3_WMM bioplex3_HCT116 WMM_only |
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