hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12354.1
Complex Portal: CPX-24373
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IKZF4 | Zinc finger protein Eos (Ikaros family zinc finger protein 4) | 5 | UniProt NCBI |
| DVL1 | Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1) | 5 | UniProt NCBI |
| ZNF74 | Zinc finger protein 74 (Zinc finger protein 520) (hZNF7) | 5 | UniProt NCBI |
| RNF187 | E3 ubiquitin-protein ligase RNF187 (EC 2.3.2.27) (RING domain AP1 coactivator 1) (RACO-1) (RING finger protein 187) (RING-type E3 ubiquitin transferase RNF187) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5441 | 0.049938562206 | 0.25 | IKZF4 | NRG1-IKZF4 complex |
| CORUM:6693 | 0.049938562206 | 0.25 | DVL1 | DVL1-PI4K2A complex |
| CORUM:7158 | 0.049938562206 | 0.25 | DVL1 | TSC2-DVL complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DVL1 | ZNF74 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IKZF4 | ZNF74 | 0.899 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| RNF187 | ZNF74 | 0.857 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| RNF187 | DVL1 | 0.076 | 0.178 | bioplex3_WMM WMM_only |
Related Complexes