hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12355.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | 5 | UniProt NCBI |
| HINT2 | Adenosine 5'-monophosphoramidase HINT2 (EC 3.9.1.-) (HINT-3) (HIT-17kDa) (Histidine triad nucleotide-binding protein 2, mitochondrial) (HINT-2) (PKCI-1-related HIT protein) | 5 | UniProt NCBI |
| ARHGDIA | Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:404 | 0.0249718442456 | 0.333333333333 | IDH1 | Isocitrate dehydrogenase [NADP], cytoplasmic |
| REAC:R-HSA-2978092 | 0.0498224659464 | 0.333333333333 | IDH1 | Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate |
| REAC:R-HSA-389542 | 0.0498224659464 | 0.333333333333 | IDH1 | NADPH regeneration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IDH1 | ARHGDIA | 0.959 | 0.22 | bioplex_WMM Guru bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| IDH1 | HINT2 | 0.82 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| ARHGDIA | HINT2 | 0.027 | 0.108 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes