hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12369.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPATA2 | Spermatogenesis-associated protein 2 | 5 | UniProt NCBI |
| CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) | 5 | UniProt NCBI |
| FGL2 | Fibroleukin (Fibrinogen-like protein 2) (pT49) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6296 | 3.41752350426e-06 | 0.666666666667 | SPATA2 CYLD | SPATA2-CYLD complex |
| REAC:R-HSA-5357786 | 0.00188000535098 | 0.666666666667 | SPATA2 CYLD | TNFR1-induced proapoptotic signaling |
| REAC:R-HSA-5357956 | 0.0033773260227 | 0.666666666667 | SPATA2 CYLD | TNFR1-induced NF-kappa-B signaling pathway |
| GO:1990108 | 0.00421361424067 | 0.666666666667 | SPATA2 CYLD | protein linear deubiquitination |
| REAC:R-HSA-5357905 | 0.00643790104829 | 0.666666666667 | SPATA2 CYLD | Regulation of TNFR1 signaling |
| KEGG:04217 | 0.00706776241177 | 0.666666666667 | SPATA2 CYLD | Necroptosis |
| REAC:R-HSA-75893 | 0.00937397262456 | 0.666666666667 | SPATA2 CYLD | TNF signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CYLD | FGL2 | 0.954 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FGL2 | SPATA2 | 0.927 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CYLD | SPATA2 | 0.366 | 0.088 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes