hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12378.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNB2 | Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2) | 5 | UniProt NCBI |
| KCNF1 | Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1) | 5 | UniProt NCBI |
| MTHFR | Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) | 5 | UniProt NCBI |
| KCNG4 | Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 3.64404491129e-06 | 0.75 | KCNG4 KCNB2 KCNF1 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 6.40033583955e-05 | 0.75 | KCNG4 KCNB2 KCNF1 | Potassium Channels |
| REAC:R-HSA-112316 | 0.00603406960129 | 0.75 | KCNG4 KCNB2 KCNF1 | Neuronal System |
| GO:0005249 | 0.00751763182363 | 0.75 | KCNG4 KCNB2 KCNF1 | voltage-gated potassium channel activity |
| GO:0008076 | 0.00951168180783 | 0.75 | KCNG4 KCNB2 KCNF1 | voltage-gated potassium channel complex |
| GO:0005267 | 0.0137962469792 | 0.75 | KCNG4 KCNB2 KCNF1 | potassium channel activity |
| GO:0034705 | 0.0137962469792 | 0.75 | KCNG4 KCNB2 KCNF1 | potassium channel complex |
| GO:0022843 | 0.0339114962397 | 0.75 | KCNG4 KCNB2 KCNF1 | voltage-gated monoatomic cation channel activity |
| WP:WP1495 | 0.0373138951921 | 0.25 | MTHFR | Glycine metabolism |
| GO:0015079 | 0.0378152735667 | 0.75 | KCNG4 KCNB2 KCNF1 | potassium ion transmembrane transporter activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNB2 | KCNG4 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNB2 | KCNF1 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KCNF1 | MTHFR | 0.878 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KCNB2 | MTHFR | 0.117 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes