hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12388.1
Complex Portal: CPX-13717
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ETFB | Electron transfer flavoprotein subunit beta (Beta-ETF) | 5 | UniProt NCBI |
| PF4 | Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)] | 5 | UniProt NCBI |
| ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) (Medium chain acyl-CoA dehydrogenase) (MCADH) | 5 | UniProt NCBI |
| C8orf82 | UPF0598 protein C8orf82 | 2 | UniProt NCBI |
| ETFA | Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) | 5 | UniProt NCBI |
| ETFRF1 | Electron transfer flavoprotein regulatory factor 1 (LYR motif-containing protein 5) | 4 | UniProt NCBI |
| NNT | NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001325 | 0.00768171284681 | 0.4 | ETFB NNT | Hypoglycemic coma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ETFRF1 | ETFB | 1.0 | 0.184 |
mutually_exclusive (P13804)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ETFRF1 | ETFA | 1.0 | 0.152 |
mutually_exclusive (P38117)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ETFB | ETFA | 1.0 | 0.95 |
mutually_exclusive (Q6IPR1)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| C8orf82 | ETFA | 0.998 | 0.126 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| C8orf82 | ETFB | 0.988 | 0.124 |
mutually_exclusive (P13804)
structurally_consistent (dimer) |
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PF4 | ETFRF1 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ETFRF1 | C8orf82 | 0.946 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| ETFA | NNT | 0.861 | 0.49 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM | |
| ACADM | ETFA | 0.849 | 0.492 |
structurally_consistent (P38117)
|
bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM fraction boldt_WMM treiber_WMM |
| ACADM | ETFB | 0.817 | 0.426 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM fraction treiber_WMM |
| C8orf82 | NNT | 0.155 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACADM | NNT | 0.083 | 0.276 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ETFB | NNT | 0.048 | 0.24 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ETFRF1 | NNT | 0.034 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| PF4 | ETFA | 0.033 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ACADM | ETFRF1 | 0.018 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PF4 | ETFB | 0.017 | bioplex3_HEK293 WMM_only | ||
| ACADM | C8orf82 | 0.015 | 0.098 |
mutually_exclusive (P38117)
|
bioplex_WMM bioplex3_WMM WMM_only |
| ACADM | PF4 | 0.006 | bioplex3_HEK293 WMM_only |
Related Complexes