hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12401.1
Complex Portal: CPX-23290
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CA2 | Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69) | 5 | UniProt NCBI |
| GSR | Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7) | 5 | UniProt NCBI |
| TPI1 | Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Methylglyoxal synthase) (EC 4.2.3.3) (Triose-phosphate isomerase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001903 | 0.0189203502844 | 1.0 | CA2 TPI1 GSR | Anemia |
| KEGG:01100 | 0.0189521995452 | 1.0 | CA2 TPI1 GSR | Metabolic pathways |
| HP:0001877 | 0.0249404281241 | 1.0 | CA2 TPI1 GSR | Abnormal erythrocyte morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GSR | CA2 | 0.946 | 0.124 | bioplex_WMM bioplex3_WMM fraction | |
| TPI1 | CA2 | 0.828 | 0.18 | bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM treiber_WMM | |
| GSR | TPI1 | 0.24 | 0.282 | bioplex_WMM bioplex3_WMM fraction treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CA2 | huMAP3_12401.1 huMAP3_13322.1 huMAP3_14033.1 huMAP3_14359.1 |
| GSR | huMAP3_04290.1 huMAP3_12401.1 huMAP3_13322.1 huMAP3_14033.1 huMAP3_14359.1 |
| TPI1 | huMAP3_12042.1 huMAP3_12401.1 huMAP3_13322.1 |