hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12411.1
Complex Portal: CPX-24809
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INVS | Inversin (Inversion of embryo turning homolog) (Nephrocystin-2) | 5 | UniProt NCBI |
| EXT2 | Exostosin-2 (EC 2.4.1.224) (Exostosin glycosyltransferase 2) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00534 | 0.0498575241799 | 0.5 | EXT2 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
| CORUM:6881 | 0.0499419797295 | 0.5 | EXT2 | EXT1-EXT2 complex |
| HP:0005976 | 0.0499436884913 | 0.5 | INVS | Hyperkalemic metabolic acidosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| INVS | EXT2 | 0.801 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| INVS | huMAP3_01398.1 huMAP3_06707.1 huMAP3_06963.1 huMAP3_12411.1 huMAP3_13855.1 |
| EXT2 | huMAP3_07431.1 huMAP3_08802.1 huMAP3_09327.1 huMAP3_12411.1 |