hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12486.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NRP1 | Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304) | 5 | UniProt NCBI |
| TMEM116 | Transmembrane protein 116 | 2 | UniProt NCBI |
| ODF2 | Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0320883 | 4.41377667959e-05 | 1.0 | TMEM116 NRP1 ODF2 | nasopharynx; ciliated cells (tip of cilia)[High] |
| HPA:0060883 | 0.000146618015384 | 1.0 | TMEM116 NRP1 ODF2 | bronchus; ciliated cells (tip of cilia)[High] |
| HPA:0320882 | 0.000344777688661 | 1.0 | TMEM116 NRP1 ODF2 | nasopharynx; ciliated cells (tip of cilia)[>=Medium] |
| HPA:0210883 | 0.000378947171693 | 1.0 | TMEM116 NRP1 ODF2 | fallopian tube; ciliated cells (tip of cilia)[High] |
| HPA:0320881 | 0.000555039484136 | 1.0 | TMEM116 NRP1 ODF2 | nasopharynx; ciliated cells (tip of cilia)[>=Low] |
| HPA:0060882 | 0.00102950919037 | 1.0 | TMEM116 NRP1 ODF2 | bronchus; ciliated cells (tip of cilia)[>=Medium] |
| HPA:0060881 | 0.00181631660099 | 1.0 | TMEM116 NRP1 ODF2 | bronchus; ciliated cells (tip of cilia)[>=Low] |
| HPA:0210882 | 0.00267633147099 | 1.0 | TMEM116 NRP1 ODF2 | fallopian tube; ciliated cells (tip of cilia)[>=Medium] |
| HPA:0210881 | 0.00503325048482 | 1.0 | TMEM116 NRP1 ODF2 | fallopian tube; ciliated cells (tip of cilia)[>=Low] |
| HPA:0320863 | 0.00771742050544 | 0.666666666667 | TMEM116 ODF2 | nasopharynx; ciliated cells (cilia axoneme)[High] |
| CORUM:5731 | 0.0249718442456 | 0.333333333333 | NRP1 | NRP1-VEGFC complex, heparin dependent |
| HPA:0320862 | 0.0305730371719 | 0.666666666667 | TMEM116 ODF2 | nasopharynx; ciliated cells (cilia axoneme)[>=Medium] |
| WP:WP5065 | 0.0331010360575 | 0.333333333333 | NRP1 | SARS CoV 2 altering angiogenesis via NRP1 |
| HPA:0320861 | 0.0389182516915 | 0.666666666667 | TMEM116 ODF2 | nasopharynx; ciliated cells (cilia axoneme)[>=Low] |
| WP:WP4846 | 0.0496447587094 | 0.333333333333 | NRP1 | SARS CoV 2 and COVID 19 pathway |
| CORUM:3104 | 0.0499402709677 | 0.333333333333 | NRP1 | ITGB1-NRP1 complex |
| CORUM:5658 | 0.0499402709677 | 0.333333333333 | NRP1 | Nrp1-PlexinD1 complex |
| CORUM:5668 | 0.0499402709677 | 0.333333333333 | NRP1 | PlexinA1-NRP1 complex |
| CORUM:5669 | 0.0499402709677 | 0.333333333333 | NRP1 | PlexinA3-Nrp1 complex |
| CORUM:5670 | 0.0499402709677 | 0.333333333333 | NRP1 | PlexinB1-Nrp1 complex |
| CORUM:5689 | 0.0499402709677 | 0.333333333333 | NRP1 | SEMA6D-PlexinA1-NRP1 complex |
| CORUM:5734 | 0.0499402709677 | 0.333333333333 | NRP1 | NRP1-VEGFD complex, heparin dependent |
| CORUM:5745 | 0.0499402709677 | 0.333333333333 | NRP1 | PlexinA1-NRP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ODF2 | NRP1 | 0.947 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NRP1 | TMEM116 | 0.915 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NRP1 | huMAP3_05202.1 huMAP3_05688.1 huMAP3_10231.1 huMAP3_12486.1 huMAP3_14227.1 |
| TMEM116 | huMAP3_12486.1 huMAP3_14227.1 |
| ODF2 | huMAP3_02687.1 huMAP3_05924.1 huMAP3_07133.1 huMAP3_12486.1 huMAP3_13433.1 |