hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12502.1
Complex Portal: CPX-18073
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ALDH1B1 | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) | 5 | UniProt NCBI |
| HIGD1C | HIG1 domain family member 1C | 4 | UniProt NCBI |
| ALDH2 | Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00340 | 8.0106389994e-05 | 0.666666666667 | ALDH1B1 ALDH2 | Histidine metabolism |
| KEGG:00770 | 0.000103747375292 | 0.666666666667 | ALDH1B1 ALDH2 | Pantothenate and CoA biosynthesis |
| KEGG:00053 | 0.00017617774418 | 0.666666666667 | ALDH1B1 ALDH2 | Ascorbate and aldarate metabolism |
| KEGG:00410 | 0.000267637530439 | 0.666666666667 | ALDH1B1 ALDH2 | beta-Alanine metabolism |
| REAC:R-HSA-71384 | 0.000374861161166 | 0.666666666667 | ALDH1B1 ALDH2 | Ethanol oxidation |
| KEGG:00380 | 0.000402489716698 | 0.666666666667 | ALDH1B1 ALDH2 | Tryptophan metabolism |
| KEGG:00071 | 0.000594396930969 | 0.666666666667 | ALDH1B1 ALDH2 | Fatty acid degradation |
| KEGG:00330 | 0.000688034410789 | 0.666666666667 | ALDH1B1 ALDH2 | Arginine and proline metabolism |
| KEGG:00620 | 0.000688034410789 | 0.666666666667 | ALDH1B1 ALDH2 | Pyruvate metabolism |
| KEGG:00280 | 0.000788502734463 | 0.666666666667 | ALDH1B1 ALDH2 | Valine, leucine and isoleucine degradation |
| KEGG:00561 | 0.00104947736992 | 0.666666666667 | ALDH1B1 ALDH2 | Glycerolipid metabolism |
| KEGG:00310 | 0.00125862804941 | 0.666666666667 | ALDH1B1 ALDH2 | Lysine degradation |
| KEGG:00010 | 0.00143958269844 | 0.666666666667 | ALDH1B1 ALDH2 | Glycolysis / Gluconeogenesis |
| KEGG:04936 | 0.00578906402762 | 0.666666666667 | ALDH1B1 ALDH2 | Alcoholic liver disease |
| KEGG:01240 | 0.00676143238566 | 0.666666666667 | ALDH1B1 ALDH2 | Biosynthesis of cofactors |
| REAC:R-HSA-211945 | 0.019882541548 | 0.666666666667 | ALDH1B1 ALDH2 | Phase I - Functionalization of compounds |
| WP:WP4966 | 0.0496447587094 | 0.333333333333 | ALDH2 | Fluoroacetic acid toxicity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALDH2 | ALDH1B1 | 0.993 | 0.268 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM treiber_WMM | |
| ALDH1B1 | HIGD1C | 0.889 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ALDH2 | HIGD1C | 0.026 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ALDH1B1 | huMAP3_05942.1 huMAP3_09161.1 huMAP3_10569.1 huMAP3_10794.1 huMAP3_12502.1 |
| HIGD1C | huMAP3_12502.1 huMAP3_15086.1 |
| ALDH2 | huMAP3_03117.1 huMAP3_04242.1 huMAP3_05942.1 huMAP3_06207.1 huMAP3_10569.1 huMAP3_12502.1 huMAP3_13307.1 huMAP3_15040.1 |