hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12522.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAX | Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) | 5 | UniProt NCBI |
| MXI1 | Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11) | 5 | UniProt NCBI |
| MXD3 | Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx) | 5 | UniProt NCBI |
| MXD4 | Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4) | 3 | UniProt NCBI |
| DNAH6 | Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) | 5 | UniProt NCBI |
| MYC | Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2655 | 1.70876175213e-05 | 0.333333333333 | MYC MAX | MYC-MAX complex |
| CORUM:3052 | 1.70876175213e-05 | 0.333333333333 | MYC MAX | MYC-MAX complex |
| CORUM:2653 | 0.000102488289015 | 0.333333333333 | MYC MAX | MYC-MAX-KAT2A-TRRAP complex |
| WP:WP5380 | 0.000388463387533 | 0.5 | MXD3 MAX MYC | 5q35 copy number variation |
| REAC:R-HSA-1362277 | 0.00393892248474 | 0.333333333333 | MYC MAX | Transcription of E2F targets under negative control by DREAM complex |
| WP:WP400 | 0.00436073489596 | 0.333333333333 | MYC MAX | p38 MAPK signaling pathway |
| GO:0071943 | 0.00702301080125 | 0.333333333333 | MYC MAX | Myc-Max complex |
| REAC:R-HSA-1538133 | 0.00835477835936 | 0.333333333333 | MYC MAX | G0 and Early G1 |
| WP:WP3651 | 0.0164862310333 | 0.333333333333 | MYC MAX | Pathways affected in adenoid cystic carcinoma |
| KEGG:05222 | 0.0261678409889 | 0.333333333333 | MYC MAX | Small cell lung cancer |
| WP:WP23 | 0.0283311425678 | 0.333333333333 | MYC MAX | B cell receptor signaling pathway |
| WP:WP4658 | 0.0388355255908 | 0.333333333333 | MYC MAX | Small cell lung cancer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAX | MXD3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MAX | MXI1 | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAX | MYC | 0.997 | 0.472 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| MAX | MXD4 | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MXI1 | MXD3 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MAX | DNAH6 | 0.97 | 0.046 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| MXI1 | MXD4 | 0.946 | bioplex3_WMM WMM_only | |
| MXD4 | MYC | 0.946 | bioplex3_WMM WMM_only | |
| MXI1 | MYC | 0.757 | bioplex3_WMM WMM_only |
Related Complexes