hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12549.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CPA5 | Carboxypeptidase A5 (EC 3.4.17.-) | 4 | UniProt NCBI |
| EPHA4 | Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK) | 5 | UniProt NCBI |
| CYP1A2 | Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2646 | 0.0165527833611 | 0.333333333333 | CYP1A2 | Lidocaine metabolism |
| KEGG:00232 | 0.0278821167741 | 0.333333333333 | CYP1A2 | Caffeine metabolism |
| WP:WP2542 | 0.0331010360575 | 0.333333333333 | CYP1A2 | Sulindac metabolic pathway |
| WP:WP3633 | 0.0331010360575 | 0.333333333333 | CYP1A2 | Caffeine and theobromine metabolism |
| WP:WP694 | 0.0331010360575 | 0.333333333333 | CYP1A2 | Arylamine metabolism |
| REAC:R-HSA-211957 | 0.0498224659464 | 0.333333333333 | CYP1A2 | Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CPA5 | EPHA4 | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CYP1A2 | EPHA4 | 0.935 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CPA5 | huMAP3_04354.1 huMAP3_10558.1 huMAP3_12549.1 huMAP3_13373.1 |
| EPHA4 | huMAP3_04354.1 huMAP3_10558.1 huMAP3_12549.1 huMAP3_13373.1 |
| CYP1A2 | huMAP3_02035.1 huMAP3_12549.1 huMAP3_13373.1 huMAP3_15172.1 |