hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12555.1
Complex Portal: CPX-11985
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UBL5 | Ubiquitin-like protein 5 | 5 | UniProt NCBI |
| IK | Protein Red (Cytokine IK) (IK factor) (Protein RER) | 5 | UniProt NCBI |
| SMU1 | WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed] | 5 | UniProt NCBI |
| WBP11 | WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1) | 5 | UniProt NCBI |
| MCRIP1 | Mapk-regulated corepressor-interacting protein 1 (Granulin-2) (Protein FAM195B) | 5 | UniProt NCBI |
| PQBP1 | Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72163 | 5.10720654207e-07 | 0.833333333333 | UBL5 PQBP1 WBP11 SMU1 IK | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 6.06851470168e-07 | 0.833333333333 | UBL5 PQBP1 WBP11 SMU1 IK | mRNA Splicing |
| REAC:R-HSA-72203 | 2.42636100074e-06 | 0.833333333333 | UBL5 PQBP1 WBP11 SMU1 IK | Processing of Capped Intron-Containing Pre-mRNA |
| REAC:R-HSA-8953854 | 0.000234756919958 | 0.833333333333 | UBL5 PQBP1 WBP11 SMU1 IK | Metabolism of RNA |
| CORUM:351 | 0.00192068311585 | 0.5 | IK SMU1 WBP11 | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| WBP11 | PQBP1 | 1.0 | 0.868 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo bioplex3_HCT116 fraction boldt_WMM | |
| SMU1 | IK | 0.998 | 0.954 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM Malo fraction boldt_WMM treiber_WMM | |
| UBL5 | PQBP1 | 0.969 | 0.068 | hein_WMM youn_WMM hein () | |
| IK | PQBP1 | 0.952 | 0.824 |
mutually_exclusive (O43447)
|
hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () |
| SMU1 | PQBP1 | 0.944 | 0.64 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| WBP11 | IK | 0.874 | 0.814 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| MCRIP1 | PQBP1 | 0.87 | 0.054 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| IK | UBL5 | 0.52 | 0.204 | hein_WMM youn_WMM WMM_only | |
| WBP11 | UBL5 | 0.515 | 0.028 | hein_WMM youn_WMM WMM_only | |
| WBP11 | SMU1 | 0.279 | 0.812 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM | |
| SMU1 | UBL5 | 0.116 | 0.242 | hein_WMM bioplex3_HEK293 bioplex () | |
| MCRIP1 | SMU1 | 0.015 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only | |
| MCRIP1 | UBL5 | 0.005 | 0.028 | youn_WMM WMM_only | |
| WBP11 | MCRIP1 | 0.005 | 0.024 | youn_WMM gupta_WMM WMM_only | |
| MCRIP1 | IK | 0.003 | 0.028 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes