hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12597.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GMFG | Glia maturation factor gamma (GMF-gamma) | 4 | UniProt NCBI |
| FN3K | Fructosamine-3-kinase (EC 2.7.1.171) (Protein-psicosamine 3-kinase FN3K) (Protein-ribulosamine 3-kinase FN3K) (EC 2.7.1.172) | 5 | UniProt NCBI |
| PRUNE1 | Exopolyphosphatase PRUNE1 (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37) (Protein prune homolog 1) (hPrune) | 5 | UniProt NCBI |
| GMFB | Glia maturation factor beta (GMF-beta) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0071846 | 0.0028092043205 | 0.5 | GMFG GMFB | actin filament debranching |
| CORUM:758 | 0.0249718442456 | 0.25 | PRUNE1 | Prune/Nm23-H1 complex |
| GO:0034316 | 0.042122686785 | 0.5 | GMFG GMFB | negative regulation of Arp2/3 complex-mediated actin nucleation |
| CORUM:756 | 0.049938562206 | 0.25 | PRUNE1 | Prune-Gelsolin complex |
| CORUM:757 | 0.049938562206 | 0.25 | PRUNE1 | Prune-GSK3beta complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GMFG | GMFB | 0.994 | 0.094 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| GMFG | FN3K | 0.993 | 0.108 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| GMFG | PRUNE1 | 0.866 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| FN3K | PRUNE1 | 0.046 | 0.104 | bioplex3_WMM WMM_only |
| GMFB | PRUNE1 | 0.012 | 0.044 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes