hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12600.1
Complex Portal: CPX-13425
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PHGDH | D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) | 5 | UniProt NCBI |
| FAM168B | Myelin-associated neurite-outgrowth inhibitor (Mani) (p20) | 5 | UniProt NCBI |
| PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5) | 5 | UniProt NCBI |
| SLC16A1 | Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1) | 5 | UniProt NCBI |
| YTHDF2 | YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2) | 5 | UniProt NCBI |
| ATAD3A | ATPase family AAA domain-containing protein 3A | 5 | UniProt NCBI |
| EID1 | EP300-interacting inhibitor of differentiation 1 (21 kDa pRb-associated protein) (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1) | 5 | UniProt NCBI |
| RBFOX2 | RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity) | 5 | UniProt NCBI |
| SLC25A3 | Solute carrier family 25 member 3 (Phosphate carrier protein, mitochondrial) (Phosphate transport protein) (PTP) | 5 | UniProt NCBI |
| SLC25A11 | Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5312 | 0.0178579187559 | 0.2 | PHGDH SLC16A1 | Metabolic pathways of fibroblasts |
| HPA:0460652 | 0.0423171558841 | 0.7 | PGAM5 ATAD3A SLC25A11 EID1 YTHDF2 PHGDH RBFOX2 | skin 1; fibroblasts[>=Medium] |
| HPA:0470682 | 0.0448868452736 | 0.8 | SLC16A1 PGAM5 ATAD3A SLC25A11 EID1 YTHDF2 PHGDH RBFOX2 | skin 2; epidermal cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC25A3 | SLC25A11 | 0.996 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | ||
| YTHDF2 | SLC25A3 | 0.992 | hein_WMM youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM WMM_only boldt_WMM | ||
| ATAD3A | SLC25A3 | 0.986 | hein_WMM bioplex_WMM Guru bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM fraction boldt_WMM | ||
| PHGDH | SLC16A1 | 0.986 | 0.118182389937 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM WMM_only boldt_WMM | |
| YTHDF2 | SLC25A11 | 0.977 | 0.032 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| SLC16A1 | SLC25A11 | 0.974 | 0.2 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM | |
| RBFOX2 | FAM168B | 0.958 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC25A3 | SLC16A1 | 0.955 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM treiber_WMM WMM_only | ||
| RBFOX2 | YTHDF2 | 0.936 | 0.112 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| PGAM5 | SLC16A1 | 0.931 | 0.156 | bioplex_WMM bioplex3_WMM boldt gupta_WMM WMM_only boldt_WMM | |
| PGAM5 | SLC25A3 | 0.921 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | ||
| EID1 | ATAD3A | 0.911 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBFOX2 | SLC25A3 | 0.9 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | ||
| PGAM5 | SLC25A11 | 0.899 | 0.105 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| EID1 | PGAM5 | 0.886 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBFOX2 | SLC16A1 | 0.859 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | |
| ATAD3A | PGAM5 | 0.858 | 0.312 | hein_WMM bioplex_WMM bioplex3_WMM boldt gupta_WMM fraction boldt_WMM | |
| ATAD3A | SLC25A11 | 0.83 | 0.128 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM WMM_only boldt_WMM | |
| RBFOX2 | SLC25A11 | 0.815 | 0.1 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| PHGDH | SLC25A11 | 0.809 | 0.242 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| PHGDH | SLC25A3 | 0.63 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM WMM_only boldt_WMM treiber_WMM | ||
| PHGDH | PGAM5 | 0.559 | 0.15 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| YTHDF2 | ATAD3A | 0.265 | 0.068 | hein_WMM youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM WMM_only boldt_WMM | |
| PHGDH | ATAD3A | 0.19 | 0.13 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM WMM_only boldt_WMM | |
| YTHDF2 | PGAM5 | 0.165 | 0.114 | youn () bioplex_WMM bioplex3_WMM boldt gupta_WMM WMM_only boldt_WMM | |
| RBFOX2 | ATAD3A | 0.161 | 0.138 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| FAM168B | SLC16A1 | 0.16 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| EID1 | SLC25A11 | 0.145 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ATAD3A | SLC16A1 | 0.133 | 0.106 | bioplex_WMM bioplex3_WMM boldt gupta_WMM WMM_only boldt_WMM | |
| YTHDF2 | PHGDH | 0.122 | 0.114 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM WMM_only boldt_WMM | |
| RBFOX2 | PGAM5 | 0.106 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | |
| FAM168B | PGAM5 | 0.097 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| YTHDF2 | SLC16A1 | 0.088 | 0.054 | youn () bioplex_WMM bioplex3_WMM boldt gupta_WMM WMM_only boldt_WMM | |
| EID1 | SLC25A3 | 0.059 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FAM168B | SLC25A11 | 0.047 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| FAM168B | YTHDF2 | 0.047 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only | |
| RBFOX2 | EID1 | 0.03 | bioplex3_HEK293 bioplex () | ||
| RBFOX2 | PHGDH | 0.021 | 0.18 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| EID1 | SLC16A1 | 0.015 | bioplex3_HEK293 bioplex () | ||
| FAM168B | ATAD3A | 0.011 | 0.074 | bioplex3_WMM WMM_only | |
| FAM168B | SLC25A3 | 0.011 | bioplex3_WMM WMM_only | ||
| EID1 | PHGDH | 0.003 | bioplex3_HEK293 bioplex () | ||
| YTHDF2 | EID1 | 0.002 | bioplex3_HEK293 bioplex () |
Related Complexes