hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12604.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCYL3 | Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) | 5 | UniProt NCBI |
| WDR45 | WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) | 5 | UniProt NCBI |
| HDAC11 | Histone deacetylase 11 (HD11) (EC 3.5.1.98) | 5 | UniProt NCBI |
| ATG2A | Autophagy-related protein 2 homolog A | 5 | UniProt NCBI |
| ATG2B | Autophagy-related protein 2 homolog B | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04140 | 0.000570106569601 | 0.6 | ATG2A WDR45 ATG2B | Autophagy - animal |
| GO:0044804 | 0.000652677252708 | 0.6 | ATG2A WDR45 ATG2B | nucleophagy |
| KEGG:04136 | 0.00196978543336 | 0.4 | ATG2A ATG2B | Autophagy - other |
| WP:WP4577 | 0.00456408083355 | 0.4 | ATG2A WDR45 | Neurodegeneration with brain iron accumulation NBIA subtypes pathway |
| GO:0000407 | 0.00475337188383 | 0.6 | ATG2A WDR45 ATG2B | phagophore assembly site |
| GO:0032266 | 0.00627040828674 | 0.6 | ATG2A WDR45 ATG2B | phosphatidylinositol-3-phosphate binding |
| KEGG:05017 | 0.0346393491085 | 0.4 | ATG2A ATG2B | Spinocerebellar ataxia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| WDR45 | ATG2B | 0.994 | 0.15 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| ATG2A | WDR45 | 0.991 | 0.12 | hein_WMM bioplex3_WMM hein () |
| ATG2B | HDAC11 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| WDR45 | HDAC11 | 0.874 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HDAC11 | SCYL3 | 0.864 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| WDR45 | SCYL3 | 0.02 | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ATG2B | SCYL3 | 0.015 | 0.132 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes