hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12623.1
Complex Portal: CPX-23186
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DDC | Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC) | 5 | UniProt NCBI |
| BSG | Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Hepatoma-associated antigen) (HAb18G) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147) | 5 | UniProt NCBI |
| SLC16A7 | Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-433692 | 2.56314262819e-05 | 1.0 | BSG SLC16A7 | Proton-coupled monocarboxylate transport |
| REAC:R-HSA-425366 | 0.00235467369443 | 1.0 | BSG SLC16A7 | Transport of bile salts and organic acids, metal ions and amine compounds |
| REAC:R-HSA-425407 | 0.0217354494871 | 1.0 | BSG SLC16A7 | SLC-mediated transmembrane transport |
| REAC:R-HSA-5619070 | 0.0499419797295 | 0.5 | BSG | Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BSG | DDC | 0.95 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC16A7 | BSG | 0.941 | 0.086 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC16A7 | DDC | 0.214 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| DDC | huMAP3_12623.1 |
| BSG | huMAP3_05673.1 huMAP3_07789.1 huMAP3_09042.1 huMAP3_12623.1 |
| SLC16A7 | huMAP3_01472.1 huMAP3_03300.1 huMAP3_05957.1 huMAP3_07901.1 huMAP3_11218.1 huMAP3_11345.1 huMAP3_11383.1 huMAP3_12623.1 |