hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12644.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADAMTS15 | A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-) | 5 | UniProt NCBI |
| FKTN | Ribitol-5-phosphate transferase FKTN (EC 2.7.8.-) (Fukutin) (Fukuyama-type congenital muscular dystrophy protein) (Ribitol-5-phosphate transferase) | 5 | UniProt NCBI |
| VCAN | Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) | 5 | UniProt NCBI |
| MYOM2 | Myomesin-2 (165 kDa connectin-associated protein) (165 kDa titin-associated protein) (M-protein) (Myomesin family member 2) | 5 | UniProt NCBI |
| HS3ST3B1 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B) | 5 | UniProt NCBI |
| EMX1 | Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) | 5 | UniProt NCBI |
| ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) | 5 | UniProt NCBI |
| CCL3 | C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))] | 5 | UniProt NCBI |
| SEMA3F | Semaphorin-3F (Sema III/F) (Semaphorin IV) (Sema IV) | 5 | UniProt NCBI |
| C1QTNF7 | Complement C1q tumor necrosis factor-related protein 7 | 2 | UniProt NCBI |
| SLIT3 | Slit homolog 3 protein (Slit-3) (Multiple epidermal growth factor-like domains protein 5) (Multiple EGF-like domains protein 5) | 5 | UniProt NCBI |
| ADAMTS17 | A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-) | 5 | UniProt NCBI |
| NDNF | Protein NDNF (Neuron-derived neurotrophic factor) | 5 | UniProt NCBI |
| PRSS23 | Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13) | 4 | UniProt NCBI |
| HOXC6 | Homeobox protein Hox-C6 (Homeobox protein CP25) (Homeobox protein HHO.C8) (Homeobox protein Hox-3C) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5083635 | 0.0338349899843 | 0.153846153846 | ADAMTS15 ADAMTS17 | Defective B3GALTL causes PpS |
| REAC:R-HSA-5173214 | 0.0375755707785 | 0.153846153846 | ADAMTS15 ADAMTS17 | O-glycosylation of TSR domain-containing proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| CCL3 | SLIT3 | 0.986 | |
| PRSS23 | C1QTNF7 | 0.985 | |
| CCL3 | HOXC6 | 0.984 | |
| HS3ST3B1 | CCL3 | 0.982 | 0.146 |
| CCL3 | NDNF | 0.978 | |
| MYOM2 | C1QTNF7 | 0.975 | |
| EMX1 | CCL3 | 0.973 | |
| ENPP2 | CCL3 | 0.972 | |
| PRSS23 | CCL3 | 0.971 | |
| VCAN | CCL3 | 0.963 | |
| ADAMTS15 | CCL3 | 0.963 | |
| C1QTNF7 | NDNF | 0.941 | |
| CCL3 | SEMA3F | 0.934 | |
| ADAMTS15 | C1QTNF7 | 0.905 | |
| C1QTNF7 | ADAMTS17 | 0.878 | |
| FKTN | CCL3 | 0.832 | |
| ADAMTS17 | CCL3 | 0.808 | |
| FKTN | SEMA3F | 0.428 | |
| SLIT3 | SEMA3F | 0.415 | |
| PRSS23 | SLIT3 | 0.415 | 0.122 |
| SLIT3 | HOXC6 | 0.415 | |
| EMX1 | SEMA3F | 0.415 | |
| HS3ST3B1 | ENPP2 | 0.415 | |
| PRSS23 | EMX1 | 0.415 | |
| ENPP2 | HOXC6 | 0.415 | |
| EMX1 | HOXC6 | 0.415 | |
| EMX1 | SLIT3 | 0.415 | |
| ENPP2 | SLIT3 | 0.415 | |
| ADAMTS15 | EMX1 | 0.415 | |
| ADAMTS15 | ENPP2 | 0.415 | |
| PRSS23 | ENPP2 | 0.415 | |
| HS3ST3B1 | EMX1 | 0.415 | |
| ADAMTS15 | SLIT3 | 0.415 | |
| HS3ST3B1 | SLIT3 | 0.415 | |
| ENPP2 | SEMA3F | 0.415 | |
| EMX1 | ENPP2 | 0.415 | |
| FKTN | ADAMTS15 | 0.391 | |
| PRSS23 | ADAMTS17 | 0.391 | |
| FKTN | HS3ST3B1 | 0.357 | |
| ADAMTS15 | NDNF | 0.319 | |
| EMX1 | NDNF | 0.278 | |
| ENPP2 | NDNF | 0.278 | |
| ADAMTS17 | SLIT3 | 0.278 | |
| SLIT3 | NDNF | 0.278 | |
| ADAMTS17 | EMX1 | 0.278 | |
| ADAMTS17 | ENPP2 | 0.278 | |
| FKTN | SLIT3 | 0.274 | |
| FKTN | EMX1 | 0.274 | |
| FKTN | ENPP2 | 0.274 | |
| HS3ST3B1 | HOXC6 | 0.274 | |
| HS3ST3B1 | SEMA3F | 0.274 | |
| ADAMTS15 | SEMA3F | 0.247 | |
| ADAMTS17 | NDNF | 0.238 | |
| PRSS23 | NDNF | 0.238 | |
| ADAMTS15 | ADAMTS17 | 0.238 | |
| PRSS23 | ADAMTS15 | 0.238 | |
| HOXC6 | SEMA3F | 0.21 | |
| VCAN | SLIT3 | 0.21 | 0.174 |
| VCAN | EMX1 | 0.21 | |
| VCAN | ENPP2 | 0.21 | |
| ADAMTS15 | HS3ST3B1 | 0.113 | |
| FKTN | ADAMTS17 | 0.102 | |
| VCAN | NDNF | 0.1 | |
| VCAN | ADAMTS17 | 0.1 | |
| ADAMTS15 | HOXC6 | 0.095 | |
| ADAMTS17 | HS3ST3B1 | 0.095 | |
| HS3ST3B1 | NDNF | 0.095 | |
| PRSS23 | HS3ST3B1 | 0.095 | 0.066 |
| FKTN | NDNF | 0.095 | |
| PRSS23 | VCAN | 0.087 | 0.128 |
| FKTN | VCAN | 0.081 | |
| NDNF | SEMA3F | 0.079 | |
| PRSS23 | SEMA3F | 0.079 | |
| FKTN | PRSS23 | 0.079 | |
| ADAMTS15 | VCAN | 0.079 | |
| VCAN | SEMA3F | 0.079 | |
| ADAMTS17 | SEMA3F | 0.078 | |
| ADAMTS17 | HOXC6 | 0.078 | |
| PRSS23 | HOXC6 | 0.078 | |
| NDNF | HOXC6 | 0.078 | |
| ADAMTS15 | MYOM2 | 0.078 | |
| VCAN | HS3ST3B1 | 0.076 | 0.052 |
| VCAN | HOXC6 | 0.076 | |
| FKTN | HOXC6 | 0.076 | |
| MYOM2 | NDNF | 0.076 | |
| PRSS23 | MYOM2 | 0.076 | |
| MYOM2 | ADAMTS17 | 0.076 |
Related Complexes